D C Kluth
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Explore the profile of D C Kluth including associated specialties, affiliations and a list of published articles.
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11
Citations
212
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Recent Articles
1.
Qi F, Adair A, Ferenbach D, Vass D, Mylonas K, Kipari T, et al.
Transplantation
. 2008 Nov;
86(9):1267-74.
PMID: 19005409
Background: Acute rejection increases the risk of late renal allograft loss with tubular atrophy, interstitial fibrosis, and microvascular rarefaction. Evidence supports a role for macrophages in promoting allograft injury, but...
2.
Kluth D
Kidney Int
. 2007 Jul;
72(3):234-6.
PMID: 17653230
Macrophages are inflammatory cells with important roles in the propagation of renal injury. More recently they have also been shown to be important in the resolution of inflammation. Wang et...
3.
Wilson H, Kluth D
Nephron Exp Nephrol
. 2003 Sep;
94(4):e113-8.
PMID: 12972709
Macrophages are key players in the development of the majority of renal diseases and are therefore ideal cellular vectors for site specifically targeting gene therapy to inflamed glomeruli. Macrophages can...
4.
Erwig L, Kluth D, Rees A
Curr Opin Nephrol Hypertens
. 2001 May;
10(3):341-7.
PMID: 11342795
This review describes recent advances in macrophage biology in the context of renal inflammation. It highlights the importance of the activated macrophage for the progression and resolution of renal disease,...
5.
Zernecke A, Weber K, Erwig L, Kluth D, Schroppel B, Rees A, et al.
J Immunol
. 2001 Apr;
166(9):5755-62.
PMID: 11313419
A sequential model involving chemokines has been proposed for leukocyte extravasation into areas of inflammation; however, site-specific aspects remain to be elucidated. Hence, we studied the role of chemokines produced...
6.
Kluth D, Ainslie C, Pearce W, Finlay S, Clarke D, Anegon I, et al.
J Immunol
. 2001 Mar;
166(7):4728-36.
PMID: 11254734
Nephrotoxic nephritis (NTN) is characterized by acute macrophage-dependent inflammation and serves as a model of human glomerulonephritis. In this study we have transfected rat macrophages with recombinant adenovirus expressing IL-4...
7.
Kluth D, Erwig L, Pearce W, Rees A
Gene Ther
. 2000 Mar;
7(3):263-70.
PMID: 10694804
In vivo gene transfer to sites of inflammatory disease provides a novel method both for studying the effects of cytokines and growth factors, and for therapeutic intervention. Macrophages play a...
8.
9.
Kluth D, Rees A
J Nephrol
. 1999 Jun;
12(2):66-75.
PMID: 10378661
Glomerulonephritis remains the leading cause of end-stage renal failure and treatments for these conditions remain non-specific and with significant side effects. The cellular and molecular basis of acute and chronic...
10.
Erwig L, Kluth D, Walsh G, Rees A
J Immunol
. 1998 Aug;
161(4):1983-8.
PMID: 9712070
The functional properties of infiltrating macrophages (Mphi) must be tightly regulated to facilitate appropriate responses to complex conditions in an inflammatory focus. This study was designed to ascertain whether uncommitted...