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D Brekine

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1.
Berkenboom G, Brekine D, Fang Z, Neve J, Fontaine J
Cardiovasc Res . 1997 Mar; 33(3):650-4. PMID: 9093535
Objective: The aim was to determine whether selenium supplementation, an important component of glutathione peroxidase, might attenuate cyclosporin (Cx)-induced vascular toxicity. Methods: Four groups of rats were treated in parallel:...
2.
Berkenboom G, Brekine D, Unger P, Richelle M, Carpentier Y, Fontaine J
Cardiovasc Drugs Ther . 1996 Jul; 10(3):379-85. PMID: 8877082
We wished to determine whether dietary supplementation with fish oil prevents the vascular toxicity of cyclosporine (Cx). In a first set of experiments, we assessed the endothelial function of aortas...
3.
Berkenboom G, Brekine D, Unger P, Gulbis B, Fontaine J
Cardiovasc Drugs Ther . 1996 Mar; 10(1):17-22. PMID: 8723166
Chronic treatment with cyclosporine A (Cx) seems to produce a decreased ability of the endothelium to secrete nitric oxide. However, its effect on the coronary arterial system remains controversial. Therefore,...
4.
Berkenboom G, Brekine D, Unger P, Grosfils K, Staroukine M, Fontaine J
Hypertension . 1995 Nov; 26(5):738-43. PMID: 7591012
To determine whether chronic angiotensin-converting enzyme (ACE) inhibition produces functional changes in the aorta normotensive rats, four groups of rats were studied in parallel for 6 weeks. Group 1 orally...
5.
Berkenboom G, Brekine D, Unger P, Gulbis B, Fontaine J
J Cardiovasc Pharmacol . 1994 Jul; 24(1):17-21. PMID: 7521483
We wished to determine whether chronic inhibition of angiotensin-converting enzyme (ACE) prevents the vascular toxicity of cyclosporine A (Cx). In aortas isolated from rats treated with ramipril [10 mg/kg/day orally...
6.
Unger P, Berkenboom G, Brekine D, Fontaine J
Eur J Pharmacol . 1993 Aug; 248(2):145-9. PMID: 8223960
The purpose of this study was to determine whether there are age-related changes in the extent of in vitro-induced nitrate tolerance. Nitroglycerin pre-exposure (10 microM for 30 min) provoked a...