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D B Wickramaratne

Explore the profile of D B Wickramaratne including associated specialties, affiliations and a list of published articles. Areas
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1.
You M, Wickramaratne D, Silva G, Chai H, Chagwedera T, Farnsworth N, et al.
J Nat Prod . 1995 Apr; 58(4):598-604. PMID: 7623038
A known aporphine alkaloid, (-)-roemerine [1], isolated from the leaves of Annona senegalensis, was found to enhance the cytotoxic response mediated by vinblastine with multidrug-resistant KB-V1 cells. In the absence...
2.
Wickramaratne D, Mar W, Chai H, Castillo J, Farnsworth N, Soejarto D, et al.
Planta Med . 1995 Feb; 61(1):80-1. PMID: 7701001
Four cytotoxic lignans were isolated from the stem bark of Bursera permollis (Burseraceae), namely, deoxypodophyllotoxin (1), beta-peltatin methyl ether (2), picro-beta-peltatin methyl ether (3), and dehydro-beta-peltatin methyl ether (4). Also...
3.
Wickramaratne D, Pengsuparp T, Mar W, Chai H, Chagwedera T, Beecher C, et al.
J Nat Prod . 1993 Dec; 56(12):2083-90. PMID: 8133298
By means of activity-directed chromatographic fractionation using cultured astrocytoma (ASK) cells, six dibenzocyclo-octadiene lignans were isolated from Steganotaenia araliacea stem bark. In addition to the most abundant analogue, steganangin [1],...
4.
Antoun M, Mendoza N, Rios Y, Proctor G, Wickramaratne D, Pezzuto J, et al.
J Nat Prod . 1993 Aug; 56(8):1423-5. PMID: 8229020
From the bulbs and leaves of Hymenocallis expansa (Amaryllidaceae), three alkaloid constituents were identified: (+)-tazettine, (+)-hippeastrine, and (-)-haemanthidine. These alkaloids demonstrated significant cytotoxicity when tested against a panel of human...
5.
Pereda-Miranda R, Mata R, Anaya A, Wickramaratne D, Pezzuto J, Kinghorn A
J Nat Prod . 1993 Apr; 56(4):571-82. PMID: 8496705
The allelopathic potential of Ipomoea tricolor (Convolvulaceae), used in Mexican traditional agriculture as a weed controller, has been demonstrated by measuring the inhibitory activity of organic extracts on seedling growth...