D B Nikolov
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Explore the profile of D B Nikolov including associated specialties, affiliations and a list of published articles.
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11
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1179
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Recent Articles
1.
Himanen J, Rajashankar K, Lackmann M, Cowan C, Henkemeyer M, Nikolov D
Nature
. 2002 Jan;
414(6866):933-8.
PMID: 11780069
The Eph family of receptor tyrosine kinases and their membrane-anchored ephrin ligands are important in regulating cell-cell interactions as they initiate a unique bidirectional signal transduction cascade whereby information is...
2.
Barton W, Lesniak J, Biggins J, Jeffrey P, Jiang J, Rajashankar K, et al.
Nat Struct Biol
. 2001 May;
8(6):545-51.
PMID: 11373625
Metabolite glycosylation is affected by three classes of enzymes: nucleotidylyltransferases, which activate sugars as nucleotide diphospho-derivatives, intermediate sugar-modifying enzymes and glycosyltransferases, which transfer the final derivatized activated sugars to aglycon...
3.
Odell M, Sriskanda V, Shuman S, Nikolov D
Mol Cell
. 2000 Dec;
6(5):1183-93.
PMID: 11106756
Chlorella virus DNA ligase is the smallest eukaryotic ATP-dependent ligase known; it has an intrinsic nick-sensing function and suffices for yeast cell growth. Here, we report the 2.0 A crystal...
4.
Himanen J, Henkemeyer M, Nikolov D
Nature
. 1998 Dec;
396(6710):486-91.
PMID: 9853759
The Eph receptors, which bind a group of cell-membrane-anchored ligands known as ephrins, represent the largest subfamily of receptor tyrosine kinases (RTKs). They are predominantly expressed in the developing and...
5.
Nikolov D, Burley S
Proc Natl Acad Sci U S A
. 1997 Jan;
94(1):15-22.
PMID: 8990153
In eukaryotes, RNA polymerase II transcribes messenger RNAs and several small nuclear RNAs. Like RNA polymerases I and III, polymerase II cannot act alone. Instead, general initiation factors [transcription factor...
6.
Nikolov D, Chen H, Halay E, Hoffman A, Roeder R, Burley S
Proc Natl Acad Sci U S A
. 1996 May;
93(10):4862-7.
PMID: 8643494
The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of...
7.
Nikolov D, Chen H, Halay E, Usheva A, Hisatake K, Lee D, et al.
Nature
. 1995 Sep;
377(6545):119-28.
PMID: 7675079
The crystal structure of the transcription factor IIB (TFIIB)/TATA box-binding protein (TBP)/TATA-element ternary complex is described at 2.7 A resolution. Core TFIIB resembles cyclin A, and recognizes the preformed TBP-DNA...
8.
Nikolov D, Burley S
Nat Struct Biol
. 1994 Sep;
1(9):621-37.
PMID: 7634102
The three-dimensional structure of a TATA box-binding protein (TBP2) from Arabidopsis thaliana has been refined at 2.1 A resolution. TBPs are general eukaryotic transcription factors that participate in initiation of...
9.
Kim J, Nikolov D, Burley S
Nature
. 1993 Oct;
365(6446):520-7.
PMID: 8413605
The three-dimensional structure of a TATA-box binding polypeptide complexed with the TATA element of the adenovirus major late promoter has been determined by X-ray crystallography at 2.25 A resolution. Binding...
10.
Burley S, Clark K, Kim J, Nikolov D
Cold Spring Harb Symp Quant Biol
. 1993 Jan;
58:123-32.
PMID: 7956022
Our X-ray crystallographic work on eukaryotic transcription factors traverses the entire length of a typical class II nuclear gene promoter, including the TATA-box-binding protein, two b/HLH/Z promoter proximal binding factors...