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D A Kasunic

Explore the profile of D A Kasunic including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 25
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Recent Articles
1.
Foster B, LoRusso P, Poplin E, Zalupski M, Valdivieso M, Wozniak A, et al.
Invest New Drugs . 1996 Jan; 13(4):321-6. PMID: 8824350
CC-1065 is a unique alkylating agent that preferentially binds in the minor groove of double-stranded DNA at adenine-thymine-rich sites. Although it has broad antitumor activity in preclinical models its development...
2.
Fleming G, Ratain M, OBrien S, Schilsky R, Hoffman P, Richards J, et al.
J Natl Cancer Inst . 1994 Mar; 86(5):368-72. PMID: 8308929
Background: Adozelesin, a synthetic analogue of the antitumor antibiotic CC-1065, is the first of a class of potent sequence-specific alkylating agents to be brought to clinical trial. In preclinical in...
3.
Shamdas G, Alberts D, Modiano M, Wiggins C, Power J, Kasunic D, et al.
Anticancer Drugs . 1994 Feb; 5(1):10-4. PMID: 8186423
During a phase I clinical and pharmacologic trial, 26 patients with refractory solid tumors were treated with increasing doses of adozelesin by brief intravenous infusion every 3 weeks. Overall, adozelesin...
4.
Weiss G, Brown T, Kuhn J, Von Hoff D, Earhart R, Adams W, et al.
Invest New Drugs . 1993 Feb; 11(1):17-27. PMID: 8349432
Thirty-five patients with advanced refractory cancer were enrolled on this phase I study of menogaril administered orally every 4 weeks at dosages ranging from 85 mg/m2 to 625 mg/m2. An...
5.
Prasher D, Kasunic D, Kushner S
J Bacteriol . 1983 Feb; 153(2):903-8. PMID: 6296059
A 17-kilobase (kb) HindIII fragment containing the structural gene for exonuclease I (sbcB) from Escherichia coli K-12 was physically and genetically characterized. The monomeric molecular weight of exonuclease I was...
6.
Kasunic D, Kushner S
Gene . 1980 Dec; 12(1-2):1-10. PMID: 7011901
The PstI and BamHI fragments, containing the HIS3 (imidazoleglycerol phosphate dehydratase) gene of yeast obtained from pYehis2, and the ColE1-derived plasmid pBR322 were ligated in vitro and used to transform...