D A Hart
Overview
Explore the profile of D A Hart including associated specialties, affiliations and a list of published articles.
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202
Citations
1948
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Recent Articles
1.
Heard B, Barton K, Abubacker S, Chung M, Martin C, Schmidt T, et al.
J Orthop Res
. 2021 Jun;
40(4):838-845.
PMID: 34061360
Posttraumatic osteoarthritis (PTOA) can develop after an injury to the knee. Previous studies have indicated that an intra-articular (IA) injection of the potent glucocorticoid dexamethasone (DEX) may significantly prevent induction...
2.
Collins K, Hart D, Seerattan R, Reimer R, Herzog W
Bone Joint Res
. 2018 Jun;
7(4):274-281.
PMID: 29922445
Objectives: Metabolic syndrome and low-grade systemic inflammation are associated with knee osteoarthritis (OA), but the relationships between these factors and OA in other synovial joints are unclear. The aim of...
3.
Heard B, Beveridge J, Atarod M, OBrien E, Rolian C, Frank C, et al.
BMC Musculoskelet Disord
. 2017 May;
18(1):212.
PMID: 28535749
Background: Many patients who undergo anterior cruciate ligament (ACL) reconstructive surgery develop post-traumatic osteoarthritis (PTOA). ACL reconstructive surgery may not fully restore pre-injury joint biomechanics, thereby resulting in further joint...
4.
Koizumi K, Ebina K, Hart D, Hirao M, Noguchi T, Sugita N, et al.
Osteoarthritis Cartilage
. 2016 Mar;
24(8):1413-22.
PMID: 26973329
Objective: To assess whether synovial mesenchymal stem cells (SMSCs) from patients with osteoarthritis (OA) or rheumatoid arthritis (RA) can be used as an alternative cell source for cartilage repair using...
5.
Egloff C, Hart D, Hewitt C, Vavken P, Valderrabano V, Herzog W
Osteoarthritis Cartilage
. 2016 Feb;
24(6):1054-60.
PMID: 26850822
Objectives: Joint instability is believed to promote early osteoarthritic changes in the knee. Inflammatory reactions are associated with cartilage degradation in osteoarthritis (OA) but their possible synergistic or additive effects...
6.
M Iqbal S, Leonard C, Regmi S, De Rantere D, Tailor P, Ren G, et al.
Sci Rep
. 2016 Jan;
6:18910.
PMID: 26752378
Proteoglycan 4 (PRG4/lubricin) is secreted by cells that reside in articular cartilage and line the synovial joint. Lubricin may play a role in modulating inflammatory responses through interaction with CD44....
7.
Collins K, Paul H, Reimer R, Seerattan R, Hart D, Herzog W
Osteoarthritis Cartilage
. 2015 Nov;
23(11):1989-98.
PMID: 26521745
Unlabelled: Osteoarthritis (OA) may result from intrinsic inflammation related to metabolic disturbance. Obesity-associated inflammation is triggered by lipopolysaccharide (LPS) derived from the gut microbiota. However, the relationship between gut microbiota,...
8.
Ehnes D, Price F, Shrive N, Hart D, Rancourt D, zur Nieden N
J Biomech
. 2015 May;
48(10):1915-21.
PMID: 25936968
Osteoblasts can be derived from embryonic stem cells (ESCs) by a 30 day differentiation process, whereupon cells spontaneously differentiate upon removal of LIF and respond to exogenously added 1,25α(OH)2 vitamin...
9.
Thornton G, Reno C, Achari Y, Morck D, Hart D
Bone Joint Res
. 2015 Mar;
4(3):38-44.
PMID: 25761872
Objectives: Ligaments which heal spontaneously have a healing process that is similar to skin wound healing. Menopause impairs skin wound healing and may likewise impair ligament healing. Our purpose in...
10.
Egloff C, Sawatsky A, Leonard T, Hart D, Valderrabano V, Herzog W
Osteoarthritis Cartilage
. 2014 Aug;
22(11):1886-93.
PMID: 25106675
Objectives: Interactions between mechanical and non-mechanical independent risk factors for the onset and progression of Osteoarthritis (OA) are poorly understood. Therefore, the goal of the present study was to investigate...