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D A Hale

Explore the profile of D A Hale including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 204
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Recent Articles
1.
Dhanireddy K, Bruno D, Weaver T, Xu H, Zhang X, Leopardi F, et al.
Am J Transplant . 2008 Nov; 9(1):124-31. PMID: 18976300
Pretransplant exposure to donor antigen is known to modulate recipient alloimmunity, and frequently results in sensitization. However, donor-specific transfusion (DST) can have a protolerant effect that is dependent on route,...
2.
Kirk A, Hale D, Swanson S, Mannon R
Am J Transplant . 2006 Apr; 6(5 Pt 1):1084-5. PMID: 16611348
No abstract available.
3.
Bolanowski A, Mannon R, Holland S, Malech H, Aschan J, Palmblad J, et al.
Am J Transplant . 2006 Feb; 6(3):636-9. PMID: 16468977
Chronic granulomatous disease (CGD) is a genetic disease caused by structural mutations in the enzyme NADPH oxidase that results in severe immunodeficiency. End-stage renal disease occurs in this patient population,...
4.
Pomfret E, Feng S, Hale D, Magee J, Mulligan M, Knechtle S
Am J Transplant . 2006 Jan; 6(2):275-80. PMID: 16426311
The 2005 American Society of Transplant Surgeons (ASTS) Winter Symposium entitled 'The Art and Science of Immunosuppression' explored ways to maximize existing immunosuppressive protocols and to develop new strategies incorporating...
5.
Mannon R, Hoffmann S, Kampen R, Cheng O, Kleiner D, Ryschkewitsch C, et al.
Am J Transplant . 2005 Nov; 5(12):2883-93. PMID: 16303001
Understanding at a molecular level, the immunologic response of polyomavirus nephropathy (PVN), a critical cause of kidney graft loss, could lead to new targets for treatment and diagnosis. We undertook...
6.
Montgomery S, Hale D, Hirshberg B, Harlan D, Kirk A
Immunol Rev . 2002 Jan; 183:214-22. PMID: 11782259
Non-human primate studies of tolerance induction strategies in solid organ transplantation represent a critical bridge between studies in rodents and humans. Our work demonstrates that strategies involving the blockade of...
7.
Hale D, Gottschalk R, Umemura A, Maki T, Monaco A
Transplantation . 2000 May; 69(7):1242-51. PMID: 10798737
Background: Induction of tolerance to organ transplants will increase graft survival and decrease patient mortality and morbidity. Radiation-induced cytoreduction/ablation followed by donor hematopoietic cell reconstitution has been the most consistently...
8.
Hale D, Gottschalk R, Maki T, Monaco A
Transplantation . 1998 Mar; 65(4):473-9. PMID: 9500619
Background: Posttransplant donor-specific bone marrow (BM) infusion in mice treated with antilymphocyte serum (ALS) induces specific unresponsiveness (tolerance) to skin allografts, which can be augmented by the adjuvant administration of...
9.
Hale D, Gottschalk R, Maki T, Monaco A
Transplantation . 1997 Oct; 64(6):897-900. PMID: 9326417
Background: The objective of our study was to determine the effectiveness of CTLA4-Ig, a novel immunosuppressive agent, in augmenting allograft survival when combined with either cyclosporine, sirolimus, donor-specific bone marrow...
10.
Hale D, Molloy M, Pearl R, Schutt D, Jaques D
Ann Surg . 1997 Mar; 225(3):252-61. PMID: 9060580
Objective: The authors present an accurate and comprehensive snapshot of appendicitis and the practice of appendectomy in the 1990s. Methods: Appendectomies were performed on 4950 patients in 147 Department of...