Cynthia Van Landingham
Overview
Explore the profile of Cynthia Van Landingham including associated specialties, affiliations and a list of published articles.
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40
Citations
190
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Recent Articles
1.
Brock W, Greene T, Van Landingham C, Gentry R
Regul Toxicol Pharmacol
. 2024 May;
150:105642.
PMID: 38735521
Isoeugenol is one of several phenylpropenoid compounds that is used as a fragrance, food flavoring agent and in aquaculture as a fish anesthetic. Carcinogenicity testing in rats and mice by...
2.
Gentry R, Greene T, Bartow H, Van Landingham C, Rodricks J, Clewell H
Crit Rev Toxicol
. 2024 Mar;
54(3):153-173.
PMID: 38470145
The Ramazzini Institute (RI) has been conducting animal carcinogenicity studies for decades, many of which have been considered by authoritative bodies to determine potential carcinogenicity in humans. Unlike other laboratories,...
3.
Linakis M, Van Landingham C, Gasparini A, Longnecker M
BMC Med Res Methodol
. 2024 Jan;
24(1):6.
PMID: 38191310
Meta-analysis poses a challenge when original study results have been expressed in a non-uniform manner, such as when regression results from some original studies were based on a log-transformed key...
4.
Campbell Jr J, Andersen M, Gentry R, Van Landingham C, Clewell 3rd H
Toxicol Lett
. 2023 Jan;
375:29-38.
PMID: 36596351
The most recent version of the octamethylcyclotetrasiloxane (D) physiologically based pharmacokinetic (model) was developed using the available kinetic studies in male and female F344 rats. Additional data, which had not...
5.
Campbell J, Clewell H, Van Landingham C, Gentry P, Keene A, Taylor M, et al.
Toxicol Sci
. 2022 Dec;
191(2):212-226.
PMID: 36453847
In earlier physiologically based pharmacokinetic (PBPK) models for manganese (Mn), the kinetics of transport of Mn into and out of tissues were primarily driven by slow rates of association and...
6.
Linakis M, Gustafson P, Allen B, Bachand A, Van Landingham C, Keast D, et al.
Environ Health
. 2022 Nov;
21(1):114.
PMID: 36419083
Background: Serum concentrations of total cholesterol and related lipid measures have been associated with serum concentrations of per- and polyfluoroalkyl substances (PFAS) in humans, even among those with only background-level...
7.
Van Landingham C, Fuller W, Schoof R
Crit Rev Toxicol
. 2020 Dec;
50(9):815-825.
PMID: 33300851
Methods proposed to address confounding variables frequently do not adequately distinguish confounding from covariation. A confounder is a variable that correlates both with the outcome and the major exposure variable....
8.
Clewell 3rd H, Campbell J, Van Landingham C, Franzen A, Yoon M, Dodd D, et al.
Inhal Toxicol
. 2020 Jan;
31(13-14):468-483.
PMID: 31992090
To develop a physiologically based pharmacokinetic (PBPK) model for chloroprene in the mouse, rat and human, relying only on data to estimate tissue metabolism rates and partitioning, and to apply...
9.
Sax S, Gentry P, Van Landingham C, Clewell H, Mundt K
Risk Anal
. 2019 Sep;
40(2):294-318.
PMID: 31524302
β-Chloroprene is used in the production of polychloroprene, a synthetic rubber. In 2010, Environmental Protection Agency (EPA) published the Integrated Risk Information System "Toxicological Review of Chloroprene," concluding that chloroprene...
10.
Yoon M, Efremenko A, Van Landingham C, Gentry P, Keene A, Taylor M, et al.
Toxicol Appl Pharmacol
. 2019 Apr;
372:1-10.
PMID: 30978397
Previously, we developed a series of physiologically based pharmacokinetic (PBPK) models for manganese (Mn) in which saturable tissue binding and dose-dependent increases in biliary excretion captured key aspects of Mn...