Cynthia R Muller
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Explore the profile of Cynthia R Muller including associated specialties, affiliations and a list of published articles.
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23
Citations
138
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Recent Articles
1.
Munoz C, Lucas D, Muller C, Martinez J, OBoyle Q, Pires I, et al.
J Appl Physiol (1985)
. 2024 Aug;
137(4):934-944.
PMID: 39143905
Unfortunately, during pathological conditions resulting in chronic hemolysis cell-free hemoglobin (Hb) is released into the circulation that releases free heme, resulting in several complications. One approach to prevent these toxicities...
2.
Munoz C, Lucas D, Muller C, Breton A, Jani V, Savla C, et al.
ACS Appl Bio Mater
. 2024 Jul;
7(8):5188-5200.
PMID: 38970152
Introduction: The demand for red blood cells (RBCs) is on the rise due to the increasing diagnosis of chronic diseases such as sickle cell anemia, malaria, and thalassemia. Despite many...
3.
Muller C, Williams A, Eaker A, Walser C, Dos Santos F, Cuddington C, et al.
Biomed Pharmacother
. 2024 May;
176:116789.
PMID: 38815289
The widespread adoption of high-calorie, high-fat, high-sucrose diets (HFHSD) has become a global health concern, particularly due to their association with cardiovascular diseases and metabolic disorders. These comorbidities increase susceptibility...
4.
Muller C, Courelli V, Govender K, Omert L, Yoshida T, Cabrales P
Life Sci
. 2024 Jan;
340:122423.
PMID: 38278347
This study aims to investigate the effects of hypoxically stored Red Blood Cells (RBCs) in a rat model of traumatic brain injury followed by severe hemorrhagic shock (HS) and resuscitation....
5.
Muller C, Courelli V, Walser C, Cuddington C, Wolfe S, Palmer A, et al.
Transl Res
. 2023 Jun;
260:83-92.
PMID: 37268039
The present study aimed to compare the ability of tense (T) and relaxed (R) quaternary state polymerized human hemoglobin (PolyhHb) to restore hemodynamics after severe trauma in a rat model,...
6.
Dufu K, Alt C, Strutt S, Partridge J, Tang T, Siu V, et al.
Br J Haematol
. 2023 Mar;
202(1):173-183.
PMID: 36960712
The pathophysiologic mechanism of sickle cell disease (SCD) involves polymerization of deoxygenated haemoglobin S (HbS), leading to red blood cell (RBC) sickling, decreased RBC deformability, microvascular obstruction, haemolysis, anaemia and...
7.
Muller C, Williams A, Walser C, Eaker A, Sandoval J, Cuddington C, et al.
Sci Rep
. 2022 Nov;
12(1):20480.
PMID: 36443351
For the past thirty years, hemoglobin-based oxygen carriers (HBOCs) have been under development as a red blood cell substitute. Side-effects such as vasoconstriction, oxidative injury, and cardiac toxicity have prevented...
8.
Williams A, Muller C, Eaker A, Belcher D, Bolden-Rush C, Palmer A, et al.
ACS Appl Bio Mater
. 2022 Jan;
3(5):2976-2985.
PMID: 35025344
Hemoglobin (Hb)-based oxygen (O) carriers (HBOCs) have been developed as an alternative to red blood cells (RBCs) for use in transfusion medicine. HBOCs have many benefits over RBCs; however, previous...
9.
Boschetti D, Muller C, Americo A, Vecchiatto B, Martucci L, Pereira R, et al.
Front Endocrinol (Lausanne)
. 2021 Dec;
12:772914.
PMID: 34970223
Obesity is associated with increased risk of several chronic diseases and the loss of disease-free years, which has increased the focus of much research for the discovery of therapy to...
10.
Belcher D, Williams A, Munoz C, Muller C, Walser C, Palmer A, et al.
J Appl Physiol (1985)
. 2021 Dec;
132(2):489-496.
PMID: 34913740
Ischemia-reperfusion injury increased vascular permeability, resulting in fluid extravasation from the intravascular compartment into the tissue space. Fluid and small protein extravasation lead to increased interstitial fluid pressure and capillary...