Cynthia L Hendrickson
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Explore the profile of Cynthia L Hendrickson including associated specialties, affiliations and a list of published articles.
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8
Citations
336
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Recent Articles
1.
Emerman A, Bowman S, Barry A, Henig N, Patel K, Gardner A, et al.
Curr Protoc Mol Biol
. 2017 Jul;
119:7.30.1-7.30.24.
PMID: 28678441
Next-generation sequencing (NGS) is a powerful tool for genomic studies, translational research, and clinical diagnostics that enables the detection of single nucleotide polymorphisms, insertions and deletions, copy number variations, and...
2.
Slatko B, Kieleczawa J, Ju J, Gardner A, Hendrickson C, Ausubel F
Curr Protoc Mol Biol
. 2011 Oct;
Chapter 7:Unit7.2.
PMID: 21987057
Beginning in the 1980s, automation of DNA sequencing has greatly increased throughput, reduced costs, and enabled large projects to be completed more easily. The development of automation technology paralleled the...
3.
Shendure J, Porreca G, Church G, Gardner A, Hendrickson C, Kieleczawa J, et al.
Curr Protoc Mol Biol
. 2011 Oct;
Chapter 7:Unit7.1.
PMID: 21987056
Efficient and cost-effective DNA sequencing technologies are critical to the progress of molecular biology. This overview of DNA sequencing strategies provides a high-level review of seven distinct approaches to DNA...
4.
Hendrickson C, Purkayastha S, Pastwa E, Neumann R, Winters T
J Nucleic Acids
. 2010 Aug;
2010:823917.
PMID: 20706599
In mammalian cells, DNA double-strand breaks (DSBs) are primarily repaired by nonhomologous end joining (NHEJ). The current model suggests that the Ku 70/80 heterodimer binds to DSB ends and recruits...
5.
Antipova A, Sokolsky T, Clouser C, Dimalanta E, Hendrickson C, Kosnopo C, et al.
J Biomol Tech
. 2009 Dec;
20(5):253-7.
PMID: 19949697
Identifying genetic variants and mutations that underlie human diseases requires development of robust, cost-effective tools for routine resequencing of regions of interest in the human genome. Here, we demonstrate that...
6.
McKernan K, Peckham H, Costa G, McLaughlin S, Fu Y, Tsung E, et al.
Genome Res
. 2009 Jun;
19(9):1527-41.
PMID: 19546169
We describe the genome sequencing of an anonymous individual of African origin using a novel ligation-based sequencing assay that enables a unique form of error correction that improves the raw...
7.
Hendrickson C, Devine K, Benner S
Nucleic Acids Res
. 2004 Apr;
32(7):2241-50.
PMID: 15107492
Standard nucleobases all present electron density as an unshared pair of electrons to the minor groove of the double helix. Many heterocycles supporting artificial genetic systems lack this electron pair....
8.
Roychowdhury A, Illangkoon H, Hendrickson C, Benner S
Org Lett
. 2004 Feb;
6(4):489-92.
PMID: 14961605
[reaction: see text] The synthesis of 2'-deoxycytidine nucleosides bearing amino and thiol groups appended to the 5-position of the nucleobase via a butynyl linker is described. The corresponding triphosphates were...