Cynthia L Baldwin
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Explore the profile of Cynthia L Baldwin including associated specialties, affiliations and a list of published articles.
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65
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1525
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Recent Articles
1.
Gillespie A, Loonie K, Lefevre L, Hope J, Baldwin C, Connelley T
J Immunol
. 2022 Nov;
209(10):1870-1879.
PMID: 36426936
Leptospira serovar Hardjo are bacterial pathogens of cattle that also cause zoonotic disease in humans. Vaccine-mediated protection against Leptospira serovar Hardjo in cattle is associated with a workshop cluster 1...
2.
Gillespie A, Loonie K, Zhang F, Prendergast J, Connelley T, Baldwin C
Mol Immunol
. 2022 Jul;
149:129-142.
PMID: 35810664
Bovine γδ T cells are distinguished by expression of WC1, hybrid pattern recognition receptors and co-receptors to the T cell receptor (TCR), or their absence. WC1 molecules bind pathogens and...
3.
Yirsaw A, Gillespie A, Zhang F, Smith T, Bickhart D, Gunasekaran K, et al.
Immunogenetics
. 2022 Feb;
74(3):347-365.
PMID: 35138437
Workshop cluster 1 (WC1) molecules are part of the scavenger receptor cysteine-rich (SRCR) superfamily and act as hybrid co-receptors for the γδ T cell receptor and as pattern recognition receptors...
4.
Damani-Yokota P, Zhang F, Gillespie A, Park H, Burnside A, Telfer J, et al.
Mol Immunol
. 2021 Dec;
142:50-62.
PMID: 34959072
γδ T cells represent a high proportion of lymphocytes in the blood of ruminants with the majority expressing lineage-specific glycoproteins from the WC1 family. WC1 receptors are coded for by...
5.
Le Page L, Baldwin C, Telfer J
Dev Comp Immunol
. 2021 Dec;
128:104334.
PMID: 34919982
Vaccination is the most effective medical strategy for disease prevention but there is a need to improve livestock vaccine efficacy. Understanding the structure of the immune system of swine, which...
6.
Teixeira A, Gillespie A, Yirsaw A, Britton E, Telfer J, Nascimento A, et al.
Infect Immun
. 2021 Oct;
90(1):e0049221.
PMID: 34694919
Pathogenic species cause leptospirosis, a neglected zoonotic disease recognized as a global public health problem. It is also the cause of the most common cattle infection that results in major...
7.
Gillespie A, Gervasi M, Sathiyaseelan T, Connelley T, Telfer J, Baldwin C
Front Immunol
. 2021 Aug;
12:712123.
PMID: 34394114
The WC1 cell surface family of molecules function as hybrid gamma delta (γδ) TCR co-receptors, augmenting cellular responses when cross-linked with the TCR, and as pattern recognition receptors, binding pathogens....
8.
Le Page L, Gillespie A, Schwartz J, Prawits L, Schlerka A, Farrell C, et al.
Dev Comp Immunol
. 2021 Jul;
125:104214.
PMID: 34329647
γδ T cells constitute a major portion of lymphocytes in the blood of both ruminants and swine. Subpopulations of swine γδ T cells have been distinguished by CD2 and CD8α...
9.
Baldwin C, Damani-Yokota P, Yirsaw A, Loonie K, Teixeira A, Gillespie A
Mol Immunol
. 2021 Mar;
134:161-169.
PMID: 33774521
Ruminant γδ T cells were discovered in the mid-1980's shortly after a novel T cell receptor (TCR) gene from murine cells was described in 1984 and the murine TCRγ gene...
10.
Gillespie A, Yirsaw A, Gunasekaran K, Smith T, Bickhart D, Turley M, et al.
Immunogenetics
. 2021 Jan;
73(2):187-201.
PMID: 33479855
Goats and cattle diverged 30 million years ago but retain similarities in immune system genes. Here, the caprine T cell receptor (TCR) gene loci and transcription of its genes were...