Cuneyt Turkes
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Explore the profile of Cuneyt Turkes including associated specialties, affiliations and a list of published articles.
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60
Citations
344
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Recent Articles
1.
Yasar U, Demir Y, Gonul I, Ozaslan M, Celik G, Turkes C, et al.
Chem Biodivers
. 2024 Dec;
:e202402893.
PMID: 39654314
Sulfonate derivatives are an essential class of compounds with diverse pharmacological applications. This study presents the synthesis and detailed characterization of six novel Schiff base sulfonate derivatives (L-L) through spectroscopic...
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Buza A, Turkes C, Arslan M, Demir Y, Dincer B, Nixha A, et al.
RSC Med Chem
. 2024 Nov;
PMID: 39493223
A series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety were conceptualized and synthesized as human carbonic anhydrase (CA) inhibitors. The synthesized small structures, denoted 7a through 7o, exhibited moderate...
4.
Kaya B, Acar Cevik U, Ciftci B, Duran H, Turkes C, Isik M, et al.
ACS Omega
. 2024 Oct;
9(42):42905-42914.
PMID: 39464438
Inhibition ofaldose reductase (AR), α-glycosidase (α-GLY), and α-amylase (α-AMY) are some of the essential targets in diabetes mellitus (DM). Here, a series of imidazo[1,2-]pyridine-based 1,3,4-thiadiazole derivatives (-) were successfully synthesized...
5.
Lolak N, Turkes C, Akocak S, Duran H, Isik M, Durgun M, et al.
Arch Biochem Biophys
. 2024 Oct;
761:110181.
PMID: 39396797
Sulfonamides, recognized as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors, are crucial in treating diverse diseases, including epilepsy, glaucoma, bacterial infections, and various pathological processes, e.g., high blood pressure, rheumatoid arthritis,...
6.
Bicer A, Caglayan C, Demir Y, Turkes C, Altundas R, Akyildiz H, et al.
Arch Biochem Biophys
. 2024 Sep;
761:110159.
PMID: 39322099
In this study, thiazole derivatives containing sulphonamide, amide, and phenyl amino groups were synthesized to protect the free amino groups of 5-methyl-4-phenyl-2-aminothiazole and 4-phenyl-2-aminothiazole. Halogenated reactions of N-protected thiazole derivatives...
7.
Turkes C
Arch Biochem Biophys
. 2024 Sep;
761:110161.
PMID: 39313142
Aldose reductase (AR, EC1.1.1.21), a member of the aldo-keto reductase family, is critically implicated in the pathogenesis of chronic complications associated with diabetes mellitus, including neuropathy, nephropathy, and retinopathy. Hyperglycemia-induced...
8.
Gulec O, Turkes C, Arslan M, Isik M, Demir Y, Duran H, et al.
Arch Biochem Biophys
. 2024 Jul;
759:110099.
PMID: 39009270
In contemporary medicinal chemistry, employing a singular small molecule to concurrently multi-target disparate molecular entities is emerging as a potent strategy in the ongoing battle against metabolic disease. In this...
9.
Koroglu Z, Kizir D, Karaman M, Demir Y, Turkes C, Beydemir S
J Biochem Mol Toxicol
. 2024 Apr;
38(4):e23702.
PMID: 38567888
Doxorubicin (DOX) is widely used in cancer treatment but the dose-related toxicity of DOX on organs including the liver limit its use. Therefore, there is great interest in combining DOX...
10.
Dawbaa S, Turkes C, Nuha D, Demir Y, Evren A, Yurttas L, et al.
J Biomol Struct Dyn
. 2024 Mar;
:1-19.
PMID: 38533902
Various carbonic anhydrase (CA) enzyme isoforms are known today. In addition to the use of CA inhibitors as diuretics, antiepileptics and antiglaucoma agents, the inhibition of other specific isoforms of...