Csilla Fazakas
Overview
Explore the profile of Csilla Fazakas including associated specialties, affiliations and a list of published articles.
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38
Citations
853
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Recent Articles
1.
Csonti K, Fazakas C, Molnar K, Wilhelm I, Krizbai I, Vegh A
Colloids Surf B Biointerfaces
. 2024 Jan;
234:113751.
PMID: 38241889
Most of the malignancies detected within the brain parenchyma are of metastatic origin. As the brain lacks classical lymphatic circulation, the primary way for metastasis relies on hematogenous routes. Dissemination...
2.
Meszaros A, Molnar K, Fazakas C, Nogradi B, Luvi A, Dudas T, et al.
Acta Neuropathol Commun
. 2023 Sep;
11(1):155.
PMID: 37749707
Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators of the tumor microenvironment. By using in vivo and in vitro brain metastasis models, as well as...
3.
Kozma M, Meszaros A, Nyul-Toth A, Molnar K, Costea L, Hernadi Z, et al.
Int J Mol Sci
. 2021 Jul;
22(11).
PMID: 34204159
By upregulation of cell adhesion molecules and secretion of proinflammatory cytokines, cells of the neurovascular unit, including pericytes and endothelial cells, actively participate in neuroinflammatory reactions. As previously shown, both...
4.
Fazakas C, Kozma M, Molnar K, Kincses A, Der A, Fejer A, et al.
Colloids Surf B Biointerfaces
. 2021 May;
204:111810.
PMID: 33965749
Despite of advances in modern therapeutics, one of the most feared complications of cancer are brain metastases, which often cause life impairing profound neurological symptoms and premature death. Breast adenocarcinoma...
5.
Molnar K, Lorinczi B, Fazakas C, Szatmari I, Fulop F, Kmetyko N, et al.
Pharmaceutics
. 2021 Jan;
13(1).
PMID: 33466551
By being an antagonist of glutamate and other receptors, kynurenic acid serves as an endogenous neuroprotectant in several pathologies of the brain. Unfortunately, systemic administration of kynurenic acid is hindered...
6.
Stefko D, Kusz N, Barta A, Kele Z, Bakacsy L, Szepesi A, et al.
J Nat Prod
. 2020 Oct;
83(10):3058-3068.
PMID: 33054206
Species in the Juncaceae accumulate different types of secondary metabolites, among them phenanthrenes and 9,10-dihydrophenanthrenes in substantial amounts. These compounds have chemotaxonomic significance and also possess interesting pharmacological activities. The...
7.
Molnar K, Meszaros A, Fazakas C, Kozma M, Gyori F, Reisz Z, et al.
Mol Oncol
. 2020 Jun;
14(9):2040-2057.
PMID: 32534480
Brain metastases are life-threatening complications of triple-negative breast cancer, melanoma, and a few other tumor types. Poor outcome of cerebral secondary tumors largely depends on the microenvironment formed by cells...
8.
Vasas A, Lajter I, Kusz N, Forgo P, Jakab G, Fazakas C, et al.
Fitoterapia
. 2020 May;
145:104610.
PMID: 32433929
Persicaria maculosa (Polygonaceae) has been used as edible and as medicinal plant since ancient times. As a result of multistep chromatographic purifications, chalcones [2'-hydroxy-3',4',6'-trimethoxychalcone (1), pashanone (2), pinostrobin chalcone (3)],...
9.
Hasko J, Fazakas C, Molnar K, Meszaros A, Patai R, Szabo G, et al.
Acta Neuropathol Commun
. 2019 Aug;
7(1):133.
PMID: 31426859
Therapeutic resistance of cerebral secondary tumours largely depends on unique aspects linked to the neurovascular unit, especially cerebral endothelial cells and astrocytes. By using advanced microscopy techniques, here we explored...
10.
Fabian E, Reglodi D, Horvath G, Opper B, Toth G, Fazakas C, et al.
Ann N Y Acad Sci
. 2019 Jul;
1455(1):160-172.
PMID: 31317557
The purpose of this study was to determine whether pituitary adenylate cyclase activating polypeptide (PACAP) could influence the neovascularization processes in hyperosmotic and oxidative stress in retinal pigment epithelial cells....