Cristina Moreno-Castro
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Explore the profile of Cristina Moreno-Castro including associated specialties, affiliations and a list of published articles.
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10
Citations
69
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Recent Articles
1.
Narvaez-Narvaez D, Duarte-Ruiz M, Jimenez-Lozano S, Moreno-Castro C, Vargas R, Nardi-Ricart A, et al.
Pharmaceuticals (Basel)
. 2023 Nov;
16(11).
PMID: 38004448
Cationic solid-lipid nanoparticles (cSLNs) have become a promising tool for gene and RNA therapies. PEGylation (PEG) is crucial in enhancing particle stability and protection. We evaluated the impact of PEG...
2.
Gonzalez-Moro I, Garcia-Etxebarria K, Mendoza L, Fernandez-Jimenez N, Mentxaka J, Olazagoitia-Garmendia A, et al.
Adv Sci (Weinh)
. 2023 Jun;
10(25):e2300063.
PMID: 37382191
Type 1 diabetes (T1D) is a complex autoimmune disease that develops in genetically susceptible individuals. Most T1D-associated single nucleotide polymorphisms (SNPs) are located in non-coding regions of the human genome....
3.
Gorgogietas V, Rajaei B, Heeyoung C, Santacreu B, Marin-Canas S, Salpea P, et al.
Diabetologia
. 2023 Mar;
66(7):1306-1321.
PMID: 36995380
Aims/hypothesis: Wolfram syndrome is a rare autosomal recessive disorder caused by pathogenic variants in the WFS1 gene. It is characterised by insulin-dependent diabetes mellitus, optic nerve atrophy, diabetes insipidus, hearing...
4.
Sune-Pou M, Limeres M, Moreno-Castro C, Hernandez-Munain C, Sune-Negre J, Cuestas M, et al.
Front Genet
. 2020 Aug;
11:731.
PMID: 32760425
Alternative splicing of pre-mRNA contributes strongly to the diversity of cell- and tissue-specific protein expression patterns. Global transcriptome analyses have suggested that >90% of human multiexon genes are alternatively spliced....
5.
Prieto-Sanchez S, Moreno-Castro C, Hernandez-Munain C, Sune C
J Cell Sci
. 2020 Feb;
133(7).
PMID: 32094262
In eukaryotes, a large amount of histones need to be synthesized during the S phase of the cell cycle to package newly synthesized DNA into chromatin. The transcription and 3'...
6.
Moreno-Castro C, Prieto-Sanchez S, Sanchez-Hernandez N, Hernandez-Munain C, Sune C
J Cell Sci
. 2019 Oct;
132(22).
PMID: 31636114
Cajal bodies are nuclear organelles involved in the nuclear phase of small nuclear ribonucleoprotein (snRNP) biogenesis. In this study, we identified the splicing factor TCERG1 as a coilin-associated factor that...
7.
Limeres M, Sune-Pou M, Prieto-Sanchez S, Moreno-Castro C, Nusblat A, Hernandez-Munain C, et al.
Colloids Surf B Biointerfaces
. 2019 Oct;
184:110533.
PMID: 31593829
Nanoparticle-mediated plasmid delivery is considered a useful tool to introduce foreign DNA into the cells for the purpose of DNA vaccination and/or gene therapy. Cationic solid-lipid nanoparticles (cSLNs) are considered...
8.
Sanchez-Hernandez N, Prieto-Sanchez S, Moreno-Castro C, Munoz-Cobo J, El Yousfi Y, Boyero-Corral S, et al.
Int J Biochem Cell Biol
. 2017 Jun;
91(Pt B):194-202.
PMID: 28600144
Studies of the spatial organization of the highly compartmentalized eukaryotic nucleus and dynamics of transcription and RNA processing within it are fundamental for fully understanding how gene expression is regulated...
9.
Sune-Pou M, Prieto-Sanchez S, Boyero-Corral S, Moreno-Castro C, El Yousfi Y, Sune-Negre J, et al.
Genes (Basel)
. 2017 Mar;
8(3).
PMID: 28245575
The tightly regulated process of precursor messenger RNA (pre-mRNA) alternative splicing (AS) is a key mechanism in the regulation of gene expression. Defects in this regulatory process affect cellular functions...
10.
Montes M, Coiras M, Becerra S, Moreno-Castro C, Mateos E, Majuelos J, et al.
PLoS One
. 2015 Oct;
10(10):e0139812.
PMID: 26462236
Here, we present evidence for a specific role of the splicing-related factor TCERG1 in regulating apoptosis in live cells by modulating the alternative splicing of the apoptotic genes Bcl-x and...