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Cristiana Barone

Explore the profile of Cristiana Barone including associated specialties, affiliations and a list of published articles. Areas
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Citations 136
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Recent Articles
1.
Crespiatico I, Zaghi M, Mastini C, DAliberti D, Mauri M, Mercado C, et al.
Blood . 2024 Jan; 143(14):1399-1413. PMID: 38194688
SETBP1 mutations are found in various clonal myeloid disorders. However, it is unclear whether they can initiate leukemia, because SETBP1 mutations typically appear as later events during oncogenesis. To answer...
2.
Barone C, Orsenigo R, Cazzola A, DErrico E, Patelli A, Quattrini G, et al.
Cancers (Basel) . 2023 Jul; 15(14). PMID: 37509285
Infant acute myeloid leukemia (AML) is a heterogeneous disease, genetically distinct from its adult counterpart. Chromosomal translocations involving the gene () are especially common in affected infants of less than...
3.
Zaghi M, Banfi F, Massimino L, Volpin M, Bellini E, Brusco S, et al.
Nat Commun . 2023 Jun; 14(1):3212. PMID: 37270547
Within the chromatin, distal elements interact with promoters to regulate specific transcriptional programs. Histone acetylation, interfering with the net charges of the nucleosomes, is a key player in this regulation....
4.
Tacconi C, Plein A, Colletto C, Villa E, Denti L, Barone C, et al.
Angiogenesis . 2022 Apr; 25(3):343-353. PMID: 35416527
Blood vessels form vast networks in all vertebrate organs to sustain tissue growth, repair and homeostatic metabolism, but they also contribute to a range of diseases with neovascularisation. It is,...
5.
Barone C, Orsenigo R, Meneveri R, Brunelli S, Azzoni E
Cells . 2022 Mar; 11(6). PMID: 35326511
Our knowledge of the complexity of the developing hematopoietic system has dramatically expanded over the course of the last few decades. We now know that, while hematopoietic stem cells (HSCs)...
6.
Azzoni E, Frontera V, Anselmi G, Rode C, James C, Deltcheva E, et al.
Cell Rep . 2021 Dec; 37(11):110103. PMID: 34910918
Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC...
7.
Pagin M, Pernebrink M, Giubbolini S, Barone C, Sambruni G, Zhu Y, et al.
Stem Cells . 2021 Mar; 39(8):1107-1119. PMID: 33739574
The Sox2 transcription factor is necessary for the long-term self-renewal of neural stem cells (NSCs). Its mechanism of action is still poorly defined. To identify molecules regulated by Sox2, and...
8.
Barone C, Buccarelli M, Alessandrini F, Pagin M, Rigoldi L, Sambruni I, et al.
Glia . 2020 Sep; 69(3):579-593. PMID: 32975900
Cancer stem cells (CSC) are essential for tumorigenesis. The transcription factor Sox2 is overexpressed in brain gliomas, and is essential to maintain CSC. In mouse high-grade glioma pHGG cells in...
9.
Mercurio S, Serra L, Motta A, Gesuita L, Sanchez-Arrones L, Inverardi F, et al.
iScience . 2019 May; 15:257-273. PMID: 31082736
Visual system development involves the formation of neuronal projections connecting the retina to the thalamic dorso-lateral geniculate nucleus (dLGN) and the thalamus to the visual cerebral cortex. Patients carrying mutations...
10.
Bertolini J, Favaro R, Zhu Y, Pagin M, Ngan C, Wong C, et al.
Cell Stem Cell . 2019 Mar; 24(3):462-476.e6. PMID: 30849367
The SOX2 transcription factor is critical for neural stem cell (NSC) maintenance and brain development. Through chromatin immunoprecipitation (ChIP) and chromatin interaction analysis (ChIA-PET), we determined genome-wide SOX2-bound regions and...