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Cristian Sirbu

Explore the profile of Cristian Sirbu including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 223
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Recent Articles
1.
Pandey R, Natarajan P, Reddy U, Du W, Sirbu C, Sissoko M, et al.
PLoS One . 2025 Jan; 20(1):e0318185. PMID: 39874307
Glioblastoma multiforme (GBM), the most prevalent primary malignant brain tumor in adults, exhibits a dismal 6.9% five-year survival rate post-diagnosis. Thymoquinone (TQ), the most abundant bioactive compound in Nigella sativa,...
2.
Hancock J, Sirbu C, Kerr P
Adv Neurobiol . 2024 Jun; 35:435-451. PMID: 38874735
Endogenous opioids and their associated receptors form a system that maintains survival by positively reinforcing behaviors that are vital to life. Cancer and cancer treatment side effects capitalize on this...
3.
Tache S, Kerr P, Sirbu C
Adv Neurobiol . 2024 Jun; 35:9-26. PMID: 38874716
The function of endogenous opioids spans from initiating behaviors that are critical for survival, to responding to rapidly changing environmental conditions. A network of interconnected systems throughout the body characterizes...
4.
Kerr P, Gregg J, Sirbu C
Adv Neurobiol . 2024 Jun; 35:1-8. PMID: 38874715
The endogenous opioid system (EOS) is complex. The line of research contributing to our current body of knowledge about this system is diverse, as are the ways in which endogenous...
5.
Sirbu C, Saxby B, McNamara C, Deal L
Front Neurol . 2022 Oct; 13:941788. PMID: 36212664
The Parkinson's Disease Activities of Daily Living, Interference, and Dependence Instrument© (PD-AID) is a patient-reported outcome (PRO) instrument, recently developed to assess the clinical benefit of Parkinson's Disease (PD) treatment....
6.
Lopez-Ortiz C, Edwards M, Natarajan P, Pacheco-Valenciana A, Nimmakayala P, Adjeroh D, et al.
Int J Mol Sci . 2022 Sep; 23(17). PMID: 36077322
The habanero pepper () is an increasingly important spice and vegetable crop worldwide because of its high capsaicin content and pungent flavor. Diets supplemented with the phytochemicals found in habanero...
7.
Du W, Sirbu C, Lucas Jr B, Jubelirer S, Khalid A, Mei L
Front Oncol . 2021 Sep; 11:667847. PMID: 34513666
Introduction: Brain metastases (BM) are associated with dismal prognosis, and there is a dearth of effective systemic therapy. In this study, patients with BM from multiple solid tumors were identified...
8.
Annie F, Sirbu C, Frazier K, Broce M, Lucas Jr B
Pharmacotherapy . 2020 Oct; 40(11):1072-1081. PMID: 33044019
Introduction: Hydroxychloroquine (HCQ) for coronavirus disease 2019 (COVID-19) is presently being used off-label or within a clinical trial. Objectives: We investigated a multinational database of patients with COVID-19 with real-world...
9.
Garcia-Lozano M, Haynes J, Lopez-Ortiz C, Natarajan P, Pena-Garcia Y, Nimmakayala P, et al.
Int J Mol Sci . 2020 Feb; 21(3). PMID: 32023882
One of the greatest impacts on the gastrointestinal microbiome is diet because the host and microbiome share the same food source. In addition, the effect of diet can diverge depending...
10.
Perla V, Nadimi M, Reddy R, Hankins G, Nimmakayala P, Harris R, et al.
PLoS One . 2018 Nov; 13(10):e0206183. PMID: 30379886
Chili peppers are an important constituent of many foods and contain medicinally valuable compounds, such as capsaicin and dihydrocapsaicin. As various dietary botanicals have anticancer properties, this study was aimed...