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Craig W Roberts

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Articles 70
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Recent Articles
11.
McPhillie M, Zhou Y, Hickman M, Gordon J, Weber C, Li Q, et al.
Front Cell Infect Microbiol . 2020 Jul; 10:203. PMID: 32626661
Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapies are needed. Herein, we create a next generation anti-apicomplexan lead compound, JAG21, a tetrahydroquinolone, with increased sp3-character to improve...
12.
Lou G, Anderluzzi G, Schmidt S, Woods S, Gallorini S, Brazzoli M, et al.
J Control Release . 2020 Jul; 325:370-379. PMID: 32619745
Self-amplifying RNA (SAM) represents a versatile tool that can be used to develop potent vaccines, potentially able to elicit strong antigen-specific humoral and cellular-mediated immune responses to virtually any infectious...
13.
Chatzikleanthous D, Cunliffe R, Carboni F, Romano M, OHagan D, Roberts C, et al.
MethodsX . 2020 Jun; 7:100942. PMID: 32551244
The well-known Toll like receptor 9 (TLR9) agonist CpG ODN has shown promising results as vaccine adjuvant in preclinical and clinical studies, however its stability and potential systemic toxicity remain...
14.
Woods S, OBrien L, Butcher W, Preston J, Georgian A, Williamson E, et al.
J Control Release . 2020 Jun; 324:644-656. PMID: 32512014
The field of brain drug delivery faces many challenges that hinder development and testing of novel therapies for clinically important central nervous system disorders. Chief among them is how to...
15.
McPhillie M, Zhou Y, El Bissati K, Dubey J, Lorenzi H, Capper M, et al.
Sci Rep . 2020 Apr; 10(1):5512. PMID: 32251362
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
16.
Chatzikleanthous D, Schmidt S, Buffi G, Paciello I, Cunliffe R, Carboni F, et al.
J Control Release . 2020 Apr; 323:125-137. PMID: 32247804
Although the well-known Toll like receptor 9 (TLR9) agonist CpGODN has shown promising results as vaccine adjuvant in preclinical and clinical studies, its in vivo stability and potential systemic toxicity...
17.
Brito C, Silva T, Castro M, Wyrwas W, Oliveira B, Fonseca B, et al.
Parasite Immunol . 2019 Dec; 42(2):e12690. PMID: 31802508
Aims: Pregnant BALB/c mice infected with a Toxoplasma gondii type II strain were used to determine how pregnancy interferes with the development of maternal immunity to T gondii and how...
18.
Hargrave K, Woods S, Millington O, Chalmers S, Westrop G, Roberts C
Front Cell Infect Microbiol . 2019 Oct; 9:309. PMID: 31572687
is capable of actively invading almost any mammalian cell type including phagocytes. Early events in phagocytic cells such as dendritic cells are not only key to establishing parasite infection, but...
19.
Lou G, Anderluzzi G, Woods S, Roberts C, Perrie Y
Eur J Pharm Biopharm . 2019 Aug; 143:51-60. PMID: 31445156
Extensive research has been undertaken to investigate the effect of liposome size in vitro and in vivo. However, it is often difficult to generate liposomes in different size ranges that...
20.
Ngo H, Zhou Y, Lorenzi H, Wang K, Kim T, Zhou Y, et al.
Sci Rep . 2019 May; 9(1):8110. PMID: 31133744
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.