Craig Midgen
Overview
Explore the profile of Craig Midgen including associated specialties, affiliations and a list of published articles.
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12
Citations
46
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Recent Articles
1.
Kobar K, Tuzi L, Fiene J, Burnley E, Galpin K, Midgen C, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Dec;
1871(3):167612.
PMID: 39643218
Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome associated with a highly penetrant cancer spectrum characterized by germline TP53 mutations. We characterized the first LFS zebrafish hotspot mutants, tp53...
2.
Prykhozhij S, Ban K, Brown Z, Kobar K, Wajnberg G, Fuller C, et al.
Data Brief
. 2024 Nov;
57:111041.
PMID: 39554546
Zebrafish () are a good model for cancer research including studies on chemotherapy treatments. We treated wild-type and deletion mutant zebrafish embryos at 24 h post-fertilization with 1 µM of...
3.
Prykhozhij S, Ban K, Brown Z, Kobar K, Wajnberg G, Fuller C, et al.
PLoS Genet
. 2024 May;
20(5):e1011290.
PMID: 38805544
Li-Fraumeni syndrome is caused by inherited TP53 tumor suppressor gene mutations. MicroRNA miR-34a is a p53 target and modifier gene. Interestingly, miR-34 triple-null mice exhibit normal p53 responses and no...
4.
Curry D, Erker C, Price V, Midgen C, Mohsin H, Sett S, et al.
CJC Pediatr Congenit Heart Dis
. 2023 Nov;
1(1):40-43.
PMID: 37969557
Pulmonary embolism in the neonate is a rare, life-threatening emergency. Risk factors for neonatal pulmonary embolism (PE) include sepsis, asphyxia, prematurity, and vascular catheterisation. We report the case of a...
5.
Kapur R, Bellizzi A, Bond S, Chen H, Han J, LeGallo R, et al.
Am J Surg Pathol
. 2021 Jan;
45(8):1047-1060.
PMID: 33492848
Congenital myenteric hypoganglionosis is a rare developmental disorder characterized clinically by severe and persistent neonatal intestinal pseudoobstruction. The diagnosis is established by the prevalence of small myenteric ganglia composed of...
6.
Curry D, Al-Sayed A, Trites J, Wheelock M, Acott P, Midgen C, et al.
Ear Nose Throat J
. 2021 Jan;
102(2):NP49-NP52.
PMID: 33491484
Desmoid-type fibromatosis (DF) is a rare soft tissue lesion with an annual incidence of 2 to 4 per million population and peak incidence occurring at approximately 4.5 years of age....
7.
Robinson B, Brock J, Midgen C, Coolen J
Clin Case Rep
. 2020 Jun;
8(5):785-789.
PMID: 32477517
In triploid pregnancies, the parental origin of the extra genome determines the phenotype and placental and fetal outcomes. Molecular genetics and placental pathology enable differentiation of molar vs nonmolar pregnancy...
8.
Brown B, Midgen C, OBrien K, El-Naggar W, Coolen J
Can J Diabetes
. 2019 Sep;
43(8):550-553.
PMID: 31548113
No abstract available.
9.
Murphy A, LeVatte T, Boudreau C, Midgen C, Gratzer P, Marshall J, et al.
Plast Reconstr Surg
. 2019 Aug;
144(5):803e-813e.
PMID: 31385893
Background: Angiotensin II engagement of angiotensin II type 1 receptor (AT1R) is implicated in fibrogenesis, with AT1R blockers used clinically to attenuate cardiac and renal fibrosis. The authors tested the...
10.
Cloney K, Steele S, Stoyek M, Croll R, Smith F, Prykhozhij S, et al.
FEBS J
. 2018 Apr;
285(11):2125-2140.
PMID: 29660852
CHARGE syndrome is linked to autosomal-dominant mutations in the CHD7 gene and results in a number of physiological and structural abnormalities, including heart defects, hearing and vision loss, and gastrointestinal...