Craig Meagher
Overview
Explore the profile of Craig Meagher including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
177
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Recent Articles
1.
Zhu M, Olson K, Kirshner J, Toroghi M, Yan H, Haber L, et al.
Clin Transl Sci
. 2022 Jan;
15(4):954-966.
PMID: 34997701
Odronextamab is a fully-human IgG4-based CD20xCD3 bispecific antibody that binds to CD3 on T cells and CD20 on B cells, triggering T-cell-mediated cytotoxicity independent of T-cell-receptor recognition. Adequate safety, tolerability,...
2.
Meagher C, Beilke J, Arreaza G, Mi Q, Chen W, Salojin K, et al.
Diabetes
. 2010 Aug;
59(11):2862-71.
PMID: 20693344
Objective: The progressive infiltration of pancreatic islets by lymphocytes is mandatory for development of autoimmune type 1 diabetes. This inflammatory process is mediated by several mediators that are potential therapeutic...
3.
DeVoss J, LeClair N, Hou Y, Grewal N, Johannes K, Lu W, et al.
J Immunol
. 2010 Mar;
184(8):4236-46.
PMID: 20237294
Sjögren's Syndrome (SS) is a human autoimmune disease characterized by immune-mediated destruction of the lacrimal and salivary glands. In this study, we show that the Aire-deficient mouse represents a new...
4.
Meagher C, Tang Q, Fife B, Bour-Jordan H, Wu J, Pardoux C, et al.
J Immunol
. 2008 Jun;
180(12):7793-803.
PMID: 18523243
Autoimmune pancreatitis (AIP) is a heterogeneous autoimmune disease in humans characterized by a progressive lymphocytic and plasmacytic infiltrate in the exocrine pancreas. In this study, we report that regulatory T...
5.
Meagher C, Arreaza G, Peters A, Strathdee C, Gilbert P, Mi Q, et al.
Diabetes
. 2007 Mar;
56(3):809-17.
PMID: 17327452
We previously reported that interleukin (IL)-4 treatment of nonobese diabetic (NOD) mice elevates intrapancreatic CCL4 expression and protects from type 1 diabetes. Here, we show that antibody neutralization of CCL4...
6.
Mi Q, Meagher C, Delovitch T
Novartis Found Symp
. 2003 Nov;
252:146-60.
PMID: 14609217
Deficiencies in NKT cell number and function mediate the development of Type 1 diabetes (TID). NKT cell activation with the CD1d ligand alpha-galactosylceramide (alpha-GalCer) corrects these deficiencies and prevents the...
7.
Mi Q, Ly D, Lamhamedi-Cherradi S, Salojin K, Zhou L, Grattan M, et al.
Diabetes
. 2003 Jul;
52(8):1967-75.
PMID: 12882912
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is expressed in different tissues and cells, including pancreas and lymphocytes, and can induce apoptosis in various tumor cells but not in most...
8.
Arreaza G, Salojin K, Yang W, Zhang J, Gill B, Mi Q, et al.
Clin Immunol
. 2003 May;
107(2):103-15.
PMID: 12763479
Activation-induced cell death (AICD) is a mechanism of homeostasis that limits the clonal expansion of autoreactive T cells and regulates central and peripheral tolerance. In nonobese diabetic (NOD) mice, defects...
9.
Grattan M, Mi Q, Meagher C, Delovitch T
Diabetes
. 2002 Jan;
51(1):215-23.
PMID: 11756344
Twenty diabetes susceptibility loci on 12 mouse chromosomes have been identified to control the development of type 1 diabetes at the level of either initiation of insulitis or progression from...