Craig M McDonald
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Explore the profile of Craig M McDonald including associated specialties, affiliations and a list of published articles.
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169
Citations
4345
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Recent Articles
1.
McDonald C, Elkins J, Dharmarajan S, Gooch K, Ciobanu T, Lansdall C, et al.
Neurol Ther
. 2024 Nov;
14(1):211-225.
PMID: 39589719
Introduction: Duchenne muscular dystrophy (DMD) is a rare, progressive, debilitating neuromuscular disease. The early childhood onset and debilitating nature of the disease necessitate decades of caretaking for most patients. Caregivers...
2.
Muntoni F, Goemans N, Posner N, Signorovitch J, Johnson M, He C, et al.
PLoS One
. 2024 Oct;
19(10):e0307118.
PMID: 39475941
Project HERCULES has developed a natural history model (NHM) of disease progression in Duchenne muscular dystrophy (DMD) that comprises eight ordered health states (two ambulatory states, one transfer state indicating...
3.
Mendell J, Muntoni F, McDonald C, Mercuri E, Ciafaloni E, Komaki H, et al.
Nat Med
. 2024 Oct;
31(1):332-341.
PMID: 39385046
Duchenne muscular dystrophy (DMD) is a rare, X-linked neuromuscular disease caused by pathogenic variants in the DMD gene that result in the absence of functional dystrophin, beginning at birth and...
4.
McDonald C, Signorovitch J, Mercuri E, Niks E, Wong B, Fillbrunn M, et al.
PLoS One
. 2024 Jun;
19(6):e0304099.
PMID: 38829874
This study examined functional trajectories of subjects during the transition phase between ambulatory and non-ambulatory Duchenne muscular dystrophy (DMD) to inform clinical trial designs for new therapeutics. Ambulatory, pulmonary, and...
5.
Schiava M, McDermott M, Broomfield J, Abrams K, Mayhew A, McDonald C, et al.
Neurology
. 2024 May;
102(10):e209206.
PMID: 38710006
Background And Objectives: Clinical trials in Duchenne muscular dystrophy (DMD) require 3-6 months of stable glucocorticoids, and the primary outcome is explored at 48-52 weeks. The factors that influence the...
6.
Mercuri E, Vilchez J, Boespflug-Tanguy O, Zaidman C, Mah J, Goemans N, et al.
Lancet Neurol
. 2024 Mar;
23(4):393-403.
PMID: 38508835
Background: Duchenne muscular dystrophy, the most common childhood muscular dystrophy, is caused by dystrophin deficiency. Preclinical and phase 2 study data have suggested that givinostat, a histone deacetylase inhibitor, might...
7.
Iff J, Done N, Tuttle E, Zhong Y, Wei F, Darras B, et al.
Muscle Nerve
. 2024 Mar;
70(1):60-70.
PMID: 38482981
Introduction/aims: Eteplirsen, approved in the US for patients with Duchenne muscular dystrophy (DMD) with exon 51 skip-amenable variants, is associated with attenuated ambulatory/pulmonary decline versus DMD natural history (NH). We...
8.
Ramli A, Liu X, Berndt K, Chuah C, Goude E, Kaethler L, et al.
Sensors (Basel)
. 2024 Feb;
24(4).
PMID: 38400313
Estimation of temporospatial clinical features of gait (CFs), such as step count and length, step duration, step frequency, gait speed, and distance traveled, is an important component of community-based mobility...
9.
Ramli A, Liu X, Berndt K, Goude E, Hou J, Kaethler L, et al.
Sensors (Basel)
. 2024 Feb;
24(4).
PMID: 38400281
Differences in gait patterns of children with Duchenne muscular dystrophy (DMD) and typically developing (TD) peers are visible to the eye, but quantifications of those differences outside of the gait...
10.
Bello L, Sabbatini D, Fusto A, Gorgoglione D, Borin G, Penzo M, et al.
J Neuromuscul Dis
. 2024 Feb;
11(2):285-297.
PMID: 38363615
Background: Dilated cardiomyopathy (DCM) is a major complication of, and leading cause of mortality in Duchenne muscular dystrophy (DMD). Its severity, age at onset, and rate of progression display wide...