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Cory H White

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Articles 33
Citations 548
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Recent Articles
1.
Shaffer M, Best K, Tang C, Liang X, Schulz S, Gonzalez E, et al.
mSystems . 2023 Aug; 8(5):e0066123. PMID: 37610205
We show that simultaneous study of stool and nasopharyngeal microbiome reveals divergent timing and patterns of maturation, suggesting that local mucosal factors may influence microbiome composition in the gut and...
2.
Datta S, Chen D, Tavares A, Reyes-Robles T, Ryu K, Khan N, et al.
Cell Chem Biol . 2023 Jul; 30(10):1313-1322.e7. PMID: 37499664
Identifying virus-host interactions on the cell surface can improve our understanding of viral entry and pathogenesis. SARS-CoV-2, the causative agent of the COVID-19 disease, uses ACE2 as a receptor to...
3.
Huth S, Oakley J, Seath C, Jacob B Geri , Trowbridge A, Parker Jr D, et al.
J Am Chem Soc . 2023 Jul; 145(30):16289-16296. PMID: 37471577
The characterization of ligand binding modes is a crucial step in the drug discovery process and is especially important in campaigns arising from phenotypic screening, where the protein target and...
4.
Parthasarathy U, Kuang Y, Thakur G, Hogan J, Wyche T, Norton Jr J, et al.
iScience . 2023 Feb; 26(2):105948. PMID: 36756375
Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Despite continued efforts to understand the pathophysiology of sepsis, no effective therapies are currently available. While singular...
5.
Bechtel T, Bertoch J, Olow A, Duich M, White C, Reyes-Robles T, et al.
Org Biomol Chem . 2022 Dec; 21(1):98-106. PMID: 36477737
Receptor-ligand interactions play essential signaling roles within intercellular contact regions. This is particularly important within the context of the immune synapse where protein communication at the surface of physically interacting...
6.
Oslund R, Reyes-Robles T, White C, Tomlinson J, Crotty K, Bowman E, et al.
Nat Chem Biol . 2022 Jun; 18(8):850-858. PMID: 35654846
The growing appreciation of immune cell-cell interactions within disease environments has led to extensive efforts to develop immunotherapies. However, characterizing complex cell-cell interfaces in high resolution remains challenging. Thus, technologies...
7.
Ashley B, Simner C, Manousopoulou A, Jenkinson C, Hey F, Frost J, et al.
Elife . 2022 Mar; 11. PMID: 35256050
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal health outcomes. Using physiological human placental perfusion and villous explants, we investigate the role of the placenta in regulating...
8.
Swaminathan G, Citron M, Xiao J, Norton Jr J, Reens A, Topcuoglu B, et al.
Vaccines (Basel) . 2021 Nov; 9(11). PMID: 34835271
Emerging evidence demonstrates a connection between microbiome composition and suboptimal response to vaccines (vaccine hyporesponse). Harnessing the interaction between microbes and the immune system could provide novel therapeutic strategies for...
9.
Mohammadi S, Morell-Perez C, Wright C, Wyche T, White C, Sana T, et al.
Stem Cell Reports . 2021 Aug; 16(9):2364-2378. PMID: 34450035
Donor-to-donor variability in primary human organoid cultures has not been well characterized. As these cultures contain multiple cell types, there is greater concern that variability could lead to increased noise....
10.
Heinson A, Woo J, Mukim A, White C, Moesker B, Bosque A, et al.
AIDS Res Hum Retroviruses . 2020 Oct; 37(2):109-121. PMID: 33045840
Despite the considerable progress that has been made in identifying cellular factors and pathways that contribute to establishment and maintenance of the latent HIV reservoir, it remains the major obstacle...