» Authors » Cornelia M Spies

Cornelia M Spies

Explore the profile of Cornelia M Spies including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 19
Citations 430
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Maleitzke T, Wiebe E, Huscher D, Spies C, Tu J, Gaber T, et al.
Arthritis Res Ther . 2023 Aug; 25(1):140. PMID: 37542341
Background: Disruption of glucocorticoid (GC) signaling in osteoblasts results in a marked attenuation of acute antibody-induced arthritis. The role of endogenous GCs in chronic inflammatory arthritis is however not fully...
2.
Tu J, Zhang Y, Kim S, Wiebe E, Spies C, Buttgereit F, et al.
Am J Pathol . 2016 Mar; 186(5):1293-301. PMID: 26988651
The role of endogenous glucocorticoids (GCs) in rheumatoid arthritis remains unclear. Herein, we examined the role of osteoblastic GC signaling in collagen antibody-induced arthritis. Intracellular GC signaling was abrogated exclusively...
3.
Strehl C, Bijlsma J, de Wit M, Boers M, Caeyers N, Cutolo M, et al.
Ann Rheum Dis . 2016 Mar; 75(6):952-7. PMID: 26933146
There is convincing evidence for the known and unambiguously accepted beneficial effects of glucocorticoids at low dosages. However, the implementation of existing recommendations and guidelines on the management of glucocorticoid...
4.
Buttgereit F, Spies C, Bijlsma J
Clin Exp Rheumatol . 2015 Oct; 33(4 Suppl 92):S29-33. PMID: 26457359
Glucocorticoid (GC) therapy is widely accepted as effective treatment for many inflammatory conditions. However, the potential of GC to produce adverse effects may prompt both patients and prescribing doctors to...
5.
Spies C, Straub R, Cutolo M, Buttgereit F
Arthritis Res Ther . 2015 Jan; 16 Suppl 2:S3. PMID: 25608777
The hypothalamic-pituitary-adrenal (HPA) axis plays an important role in regulating and controlling immune responses. Dysfunction of the HPA axis has been implicated in the pathogenesis of rheumatoid arthritis (RA) and...
6.
Cutolo M, Spies C, Buttgereit F, Paolino S, Pizzorni C
Arthritis Res Ther . 2015 Jan; 16 Suppl 2:S1. PMID: 25608624
The management of rheumatoid arthritis (RA) is primarily based on the use of disease-modifying antirheumatic drugs (DMARDs), mainly comprising synthetic chemical compounds (that is, methotrexate or leflunomide) and biological agents...
7.
Spies C, Hoff P, Mazuch J, Gaber T, Maier B, Strehl C, et al.
Clin Exp Rheumatol . 2014 Dec; 33(1):34-43. PMID: 25535886
Objectives: The circadian rhythm of clinical symptoms in rheumatoid arthritis (RA) has been primarily attributed to circadian variations in humoral factors and hormones. In this study, we investigated circadian rhythms...
8.
Spies C, Wiebe E, Tu J, Li A, Gaber T, Huscher D, et al.
BMC Musculoskelet Disord . 2014 Feb; 15:31. PMID: 24491163
Background: The role of endogenous glucocorticoids (GC) in the initiation and maintenance of rheumatoid arthritis (RA) remains unclear. We demonstrated previously that disruption of GC signalling in osteoblasts results in...
9.
Strehl C, Gaber T, Jakstadt M, Hahne M, Hoff P, Spies C, et al.
J Fluoresc . 2013 Feb; 23(3):509-18. PMID: 23408089
Flow cytometry has become a widely-used and powerful tool for the characterization of cells according to their expression of specific proteins. However, sensitivity of this method is still limited since...
10.
Spies C, Straub R, Buttgereit F
Arthritis Res Ther . 2012 Jul; 14(3):216. PMID: 22747923
In rheumatic and other chronic inflammatory diseases, high amounts of energy for the activated immune system have to be provided and allocated by energy metabolism. In recent time many new...