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Corinna U Keber

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Articles 11
Citations 109
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Recent Articles
1.
Graf S, Keber C, Hattesohl A, Teply-Szymanski J, Hattesohl S, Guder M, et al.
J Neuroendocrinol . 2024 Jan; 36(2):e13364. PMID: 38246597
Neuroendocrine tumors of the small intestine (SI-NETs) often develop lymph node metastasis (LNM)-induced mesenteric fibrosis (MF). MF can cause intestinal obstruction as well as ischemia and render surgical resection technically...
2.
Steitz A, Schroder C, Knuth I, Keber C, Sommerfeld L, Finkernagel F, et al.
iScience . 2023 Dec; 26(12):108401. PMID: 38047087
A crucial requirement for metastasis formation in ovarian high-grade serous carcinoma (HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems of primary human cells, we discovered that...
3.
Lutz V, Hellmund V, Picard F, Raifer H, Ruckenbrod T, Klein M, et al.
Cancer Immunol Res . 2023 Feb; 11(4):421-434. PMID: 36758176
Intratumoral cytotoxic CD8+ T cells (CTL) enter a dysfunctional state characterized by expression of coinhibitory receptors, loss of effector function, and changes in the transcriptional landscape. Even though several regulators...
4.
Enukashvily N, Ponomartsev N, Ketkar A, Suezov R, Chubar A, Prjibelski A, et al.
Cell Death Dis . 2023 Jan; 14(1):19. PMID: 36635266
The abnormal tumor microenvironment (TME) often dictates the therapeutic response of cancer to chemo- and immuno-therapy. Aberrant expression of pericentromeric satellite repeats has been reported for epithelial cancers, including lung...
5.
Stark M, Nicolai M, Tatura M, Keber C, Kaufmann A, Chung H, et al.
Cancer Med . 2023 Jan; 12(7):8542-8556. PMID: 36602302
Background: Toll-like receptors (TLRs) are gaining attention for their potential to influence tumor biology both on the level of the tumor cells as well as on the level of the...
6.
Romero R, Zarzycka A, Preussner M, Fischer F, Hain T, Herrmann J, et al.
Microbiome . 2022 Sep; 10(1):158. PMID: 36171625
Background: The intestinal microbiota fundamentally guides the development of a normal intestinal physiology, the education, and functioning of the mucosal immune system. The Citrobacter rodentium-carrier model in germ-free (GF) mice...
7.
Klimovich B, Meyer L, Merle N, Neumann M, Konig A, Ananikidis N, et al.
J Exp Clin Cancer Res . 2022 Mar; 41(1):80. PMID: 35232479
Background: Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice...
8.
Keber C, Derigs M, Schultz C, Wegner M, Lingelbach S, Wischmann V, et al.
Cancer Immunol Immunother . 2022 Feb; 71(10):2381-2389. PMID: 35184226
Immune checkpoint blockade therapy is a treatment option of various metastatic cancer diseases including renal cell carcinoma (RCC). Approved antibody drugs target the co-inhibitory signaling of Programmed Cell Death Ligand-1...
9.
Repenning A, Happel D, Bouchard C, Meixner M, Verel-Yilmaz Y, Raifer H, et al.
EMBO J . 2021 May; 40(13):e106777. PMID: 33999432
The p14 protein is a well-known regulator of p53-dependent and p53-independent tumor-suppressive activities. In unstressed cells, p14 is predominantly sequestered in the nucleoli, bound to its nucleolar interaction partner NPM....
10.
Safai Zadeh E, Keber C, Dietrich C, Westhoff C, Gunter C, Beutel B, et al.
J Ultrasound Med . 2021 May; 41(3):565-574. PMID: 33955572
Purpose: To describe the perfusion patterns of peripheral pulmonary granulomatous lesions (PPGLs) by contrast-enhanced ultrasound (CEUS) and their correlation with vascularization patterns (VPs) represented by immunohistochemical (CD34) endothelial staining. Patients...