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Corinna Darian-Smith

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Recent Articles
1.
Fisher K, Garner J, Darian-Smith C
J Neurosci . 2024 Jan; 44(3). PMID: 38233220
Spinal cord injury (SCI) is devastating, with limited treatment options and variable outcomes. Most in vivo SCI research has focused on the acute and early post-injury periods, and the promotion...
2.
Fisher K, Garner J, Darian-Smith C
J Comp Neurol . 2022 Aug; 530(17):3039-3055. PMID: 35973735
Small sensory spinal injuries induce plasticity across the neuraxis, but little is understood about their effect on segmental connections or motor neuron (MN) function. Here, we begin to address this...
3.
Lucot K, Bukhari S, Webber E, Bonham T, Darian-Smith C, Montine T, et al.
Comp Med . 2022 Jul; 72(4):267-272. PMID: 35882509
Age-associated neurodegenerative changes, including amyloid β (Aβ) plaques, neurofibrillary tangles (NFTs), and amyloid angiopathy comparable to those seen in the brains of human patients with Alzheimer's disease (AD), have been...
4.
Crowley M, Lilak A, Garner J, Darian-Smith C
Behav Brain Res . 2021 Aug; 416:113533. PMID: 34453971
A long held view in the spinal cord injury field is that corticospinal terminal sprouting is needed for new connections to form, that then mediate behavioral recovery. This makes sense,...
5.
Fisher K, Garner J, Darian-Smith C
J Neurosci . 2020 Jan; 40(8):1625-1639. PMID: 31959698
The loss of sensory input following a spinal deafferentation injury can be debilitating, and this is especially true in primates when the hand is involved. Although significant recovery of function...
6.
McCann M, Fisher K, Ahloy-Dallaire J, Darian-Smith C
J Comp Neurol . 2019 Nov; 528(8):1293-1306. PMID: 31769033
The corticospinal tract (CST) is the major descending pathway controlling voluntary hand function in primates, and though less dominant, it mediates voluntary paw movements in rats. As with primates, the...
7.
Crowley M, Lilak A, Ahloy-Dallaire J, Darian-Smith C
J Comp Neurol . 2019 Feb; 527(11):1901-1912. PMID: 30707439
Meissner's corpuscles (MCs) are cutaneous mechanoreceptors found in glabrous skin and are exquisitely sensitive to light touch. Along with other receptors, they provide continuous sensory feedback that informs the execution...
8.
Fisher K, Lilak A, Garner J, Darian-Smith C
J Comp Neurol . 2018 Jul; 526(15):2373-2387. PMID: 30014461
The corticospinal tract (CST) forms the major descending pathway mediating voluntary hand movements in primates, and originates from ∼nine cortical subdivisions in the macaque. While the terminals of spared motor...
9.
Darian-Smith C, Lilak A, Garner J, Irvine K
J Neurosci . 2014 Sep; 34(37):12267-79. PMID: 25209269
The primate corticospinal tract (CST), the major descending pathway mediating voluntary hand movements, comprises nine or more functional subdivisions. The role of subcomponents other than that from primary motor cortex,...
10.
Darian-Smith C, Lilak A, Alarcon C
J Comp Neurol . 2012 Dec; 521(10):2359-72. PMID: 23239125
The corticospinal tract in the macaque and human forms the major descending pathway involved in volitional hand movements. Following a unilateral cervical dorsal root lesion, by which sensory input to...