Corine Girard-Thernier
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Explore the profile of Corine Girard-Thernier including associated specialties, affiliations and a list of published articles.
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11
Citations
158
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Recent Articles
1.
Pham T, Liagre B, Girard-Thernier C, Demougeot C
Drug Discov Today
. 2018 Feb;
23(4):871-878.
PMID: 29391126
Arginase plays an important part in l-arginine metabolism. This metalloenzyme also regulates polyamine biosynthesis, nitric oxide production and the T-cell-mediated immune response, which are all involved in the growth and...
2.
Arraki K, Totoson P, Decendit A, Badoc A, Zedet A, Jolibois J, et al.
J Nat Prod
. 2017 Aug;
80(9):2432-2438.
PMID: 28837342
The inhibition of arginase is of substantial interest for the treatment of various diseases of public health interest including cardiovascular diseases. Using an ex vivo experiment on rat aortic rings...
3.
Pudlo M, Demougeot C, Girard-Thernier C
Med Res Rev
. 2016 Nov;
37(3):475-513.
PMID: 27862081
Arginase (EC 3.5.3.1) is the bimanganese enzyme that converts L-arginine into ornithine and urea. This enzyme was discovered more than a century ago and early α-amino acids were identified as...
4.
Caoduro C, Hervouet E, Girard-Thernier C, Gharbi T, Boulahdour H, Delage-Mourroux R, et al.
Acta Biomater
. 2016 Nov;
49:36-44.
PMID: 27826000
Statement Of Significance: Efficient non-viral gene delivery is desirable, yet challenging. CNTs appear as a promising solution to penetrate into cells and successfully deliver DNA. Moreover, the field of use...
5.
Bordage S, Pham T, Zedet A, Gugglielmetti A, Nappey M, Demougeot C, et al.
Planta Med
. 2016 Oct;
83(7):647-653.
PMID: 27776374
Polyphenols are plant secondary metabolites which possess many positive effects on human health. Although these beneficial effects could be mediated through an increase in nitric oxide synthase activity, little is...
6.
Pham T, Bordage S, Pudlo M, Demougeot C, Thai K, Girard-Thernier C
Int J Mol Sci
. 2016 Oct;
17(10).
PMID: 27690022
Arginases are enzymes that are involved in many human diseases and have been targeted for new treatments. Here a series of cinnamides was designed, synthesized and evaluated in vitro and...
7.
Ngo Lemba Tom E, Girard-Thernier C, Demougeot C
Phytomedicine
. 2016 Jul;
23(10):1037-42.
PMID: 27444349
Background: Chlorogenic acid (CGA), the main polyphenol contained in coffee, is a major contributor to dietary polyphenol intake. Few studies reported its anti-hypertensive properties but the mechanisms are still indefinite....
8.
Ngo Lemba Tom E, Girard-Thernier C, Martin H, Dimo T, Alvergnas M, Nappey M, et al.
J Ethnopharmacol
. 2013 Nov;
151(1):372-9.
PMID: 24212074
Ethnopharmacological Relevance: The stem bark of Terminalia superba (TS) is widely used as a decoction by Cameroonian folk medicine for the treatment of hypertension. The aim of the present study...
9.
Senejoux F, Demougeot C, Cuciureanu M, Miron A, Cuciureanu R, Berthelot A, et al.
J Ethnopharmacol
. 2013 Apr;
147(2):536-9.
PMID: 23541934
Ethnopharmacological Relevance: Aerial parts of Heracleum sphondylium L. (HS) are used in traditional medicine to treat hypertension. To provide pharmacological basis for this use, we investigated the vasorelaxant effects of...
10.
Senejoux F, Girard-Thernier C, Berthelot A, Bevalot F, Demougeot C
Fundam Clin Pharmacol
. 2012 Jan;
27(3):262-70.
PMID: 22233502
Apocynin is a naturally occurring acetophenone widely used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. Recent data suggested that apocynin might exert NADPH oxidase-independent pharmacological properties. Among...