Constanze Schneider
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Explore the profile of Constanze Schneider including associated specialties, affiliations and a list of published articles.
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21
Citations
333
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Recent Articles
11.
Sahm M, Schneider C, Gretschel S, Kube R, Becker A, Gunther M, et al.
Chirurg
. 2021 Aug;
93(3):274-285.
PMID: 34374822
Analysis of the quality of care for colorectal cancer is an essential foundation for further development and is based on the comparison of the goals set and the actual quality...
12.
Rothenburger T, McLaughlin K, Herold T, Schneider C, Oellerich T, Rothweiler F, et al.
Commun Biol
. 2020 Jun;
3(1):324.
PMID: 32581304
The nucleoside analogue nelarabine, the prodrug of arabinosylguanine (AraG), is effective against T-cell acute lymphoblastic leukaemia (T-ALL) but not against B-cell ALL (B-ALL). The underlying mechanisms have remained elusive. Here,...
13.
Oellerich T, Schneider C, Thomas D, Knecht K, Buzovetsky O, Kaderali L, et al.
Nat Commun
. 2019 Aug;
10(1):3475.
PMID: 31375673
Hypomethylating agents decitabine and azacytidine are regarded as interchangeable in the treatment of acute myeloid leukemia (AML). However, their mechanisms of action remain incompletely understood, and predictive biomarkers for HMA...
14.
Knecht K, Buzovetsky O, Schneider C, Thomas D, Srikanth V, Kaderali L, et al.
Proc Natl Acad Sci U S A
. 2018 Oct;
115(43):E10022-E10031.
PMID: 30305425
SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase (dNTPase) that depletes cellular dNTPs in noncycling cells to promote genome stability and to inhibit retroviral and herpes viral replication. In addition to being...
15.
Schneider C, Oellerich T, Baldauf H, Schwarz S, Thomas D, Flick R, et al.
Nat Med
. 2017 Jun;
23(6):788.
PMID: 28586337
No abstract available.
16.
Schneider C, Oellerich T, Baldauf H, Schwarz S, Thomas D, Flick R, et al.
Nat Med
. 2016 Dec;
23(2):250-255.
PMID: 27991919
The nucleoside analog cytarabine (Ara-C) is an essential component of primary and salvage chemotherapy regimens for acute myeloid leukemia (AML). After cellular uptake, Ara-C is converted into its therapeutically active...
17.
Schoffer O, Schulein S, Arand G, Arnholdt H, Baaske D, Bargou R, et al.
BMC Cancer
. 2016 Dec;
16(1):936.
PMID: 27919243
Background: Over the past two decades, there has been a rising trend in malignant melanoma incidence worldwide. In 2008, Germany introduced a nationwide skin cancer screening program starting at age...
18.
Voges Y, Michaelis M, Rothweiler F, Schaller T, Schneider C, Politt K, et al.
Cell Death Dis
. 2016 Oct;
7(10):e2410.
PMID: 27735941
Resistance formation after initial therapy response (acquired resistance) is common in high-risk neuroblastoma patients. YM155 is a drug candidate that was introduced as a survivin suppressant. This mechanism was later...
19.
Lieder A, Guenzel T, Lebentrau S, Schneider C, Franzen A
Int Braz J Urol
. 2016 Sep;
43(2):202-208.
PMID: 27649110
Purpose: Renal cell carcinoma (RCC) is a malignant tumor that metastasizes early, and patients often present with metastatic disease at the time of diagnosis. The aim of our evaluation was...
20.
Grishina I, Debus K, Garcia-Limones C, Schneider C, Shresta A, Garcia C, et al.
Biochim Biophys Acta
. 2012 Oct;
1823(12):2287-96.
PMID: 23044042
Posttranslational modification of proteins by lysine acetylation regulates many biological processes ranging from signal transduction to chromatin compaction. Here we identify the acetyl-transferases CBP/p300, Tip60 and PCAF as new substrates...