Constance T Noguchi
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Explore the profile of Constance T Noguchi including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
673
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Recent Articles
1.
Yin W, Noguchi C
Cells
. 2025 Feb;
14(4).
PMID: 39996752
Erythropoietin (EPO) is a key regulator of erythrocyte production, promoting erythroid progenitor cell survival, division, and differentiation in the fetal liver and adult bone marrow. Mice lacking EPO or its...
2.
Dragojevic T, Zivkovic E, Diklic M, Ajtic O, Lazarevic M, Suboticki T, et al.
Biomed Pharmacother
. 2024 Nov;
181:117723.
PMID: 39615166
Hydroxyurea (hydroxycarbamide, HU) arrests cells in the S-phase by inhibiting ribonucleotide reductase and DNA synthesis, significantly contributing to the release of nitric oxide (NO). We investigated the involvement of inducible...
3.
Yin W, Rajvanshi P, Rogers H, Yoshida T, Kopp J, An X, et al.
Nat Commun
. 2024 Sep;
15(1):8114.
PMID: 39284834
Erythropoietin (EPO) plays a key role in energy metabolism, with EPO receptor (EpoR) expression in white adipose tissue (WAT) mediating its metabolic activity. Here, we show that male mice lacking...
4.
Upanan S, Lee J, Tunau-Spencer K, Rajvanshi P, Wright E, Noguchi C, et al.
Front Physiol
. 2024 May;
15:1352242.
PMID: 38784116
Introduction: Nitric oxide (NO) is a vasodilator gas that plays a critical role in mitochondrial respiration and skeletal muscle function. NO is endogenously generated by NO synthases: neuronal NO synthase...
5.
Lee J, Rogers H, Springer D, Noguchi C
Front Physiol
. 2024 Apr;
15:1338476.
PMID: 38628440
Erythropoietin (EPO) acts primarily in regulating red blood cell production mediated by high EPO receptor (EPOR) expression in erythroid progenitor cells. EPO activity in non-erythroid tissue is evident in mice...
6.
7.
Lee J, Dey S, Rajvanshi P, Merling R, Teng R, Rogers H, et al.
Front Cell Dev Biol
. 2023 Mar;
11:1144110.
PMID: 36895793
Erythropoietin (EPO), produced in the kidney in a hypoxia responsive manner, is required for red blood cell production. In non-erythroid tissue, EPO increases endothelial cell production of nitric oxide (NO)...
8.
Dey S, Lee J, Noguchi C
Front Pharmacol
. 2021 Oct;
12:725734.
PMID: 34603036
Erythropoietin (EPO) receptor (EPOR) determines EPO response. High level EPOR on erythroid progenitor cells gives rise to EPO regulated production of red blood cells. Animal models provide evidence for EPO...
9.
Suresh S, Wright E, Wright D, Abbott K, Noguchi C
J Bone Miner Res
. 2021 May;
36(7):1211-1219.
PMID: 33949002
Erythropoietin (EPO) is the primary regulator of bone marrow erythropoiesis. Mouse models have provided evidence that EPO also promotes bone remodeling and that EPO-stimulated erythropoiesis is accompanied by bone loss...
10.
Suresh S, Lee J, Noguchi C
FASEB J
. 2020 Jul;
34(9):11685-11697.
PMID: 32671900
Erythropoietin (EPO) regulates erythropoiesis by binding to erythropoietin receptor (Epor) on erythroid progenitor cells. Epor is also expressed on bone forming osteoblasts and bone loss accompanies EPO-stimulated erythropoiesis in mice....