Constance S Harrell
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Explore the profile of Constance S Harrell including associated specialties, affiliations and a list of published articles.
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11
Citations
310
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Recent Articles
1.
Rowson S, Harrell C, Bekhbat M, Gangavelli A, Wu M, Kelly S, et al.
Front Psychiatry
. 2016 Jul;
7:102.
PMID: 27378953
Highly active antiretroviral therapy (HAART) has improved prognosis for people living with HIV (PLWH) and dramatically reduced the incidence of AIDS. However, even when viral load is controlled, PLWH develop...
2.
Harrell C, Burgado J, Kelly S, Johnson Z, Neigh G
Psychoneuroendocrinology
. 2015 Sep;
62:252-64.
PMID: 26356038
Fructose consumption, which promotes insulin resistance, hypertension, and dyslipidemia, has increased by over 25% since the 1970s. In addition to metabolic dysregulation, fructose ingestion stimulates the hypothalamic-pituitary-adrenal (HPA) axis leading...
3.
Harrell C, Rowson S, Neigh G
Neurosci Lett
. 2015 Jun;
600:75-9.
PMID: 26037418
While both glucocorticoids (the principal output of the hypothalamic-pituitary-adrenal axis) and oxidative stress have been implicated in outcomes due to an excessive or prolonged stress response, the precise mechanisms linking...
4.
Nemeth C, Glasper E, Harrell C, Malviya S, Otis J, Neigh G
PLoS One
. 2014 Oct;
9(10):e108399.
PMID: 25271421
Adolescents living with human immunodeficiency virus (HIV) comprise approximately 12% of the HIV-positive population worldwide. HIV-positive adolescents experience a higher rate of clinical depression, a greater risk of sexual and...
5.
Burgado J, Harrell C, Eacret D, Reddy R, Barnum C, Tansey M, et al.
Behav Brain Res
. 2014 Sep;
275:120-5.
PMID: 25200517
Psychological stress can have devastating and lasting effects on a variety of behaviors, especially those associated with mental illnesses such as anxiety and depression. Animal models of chronic stress are...
6.
Kelly S, Harrell C, Neigh G
Physiol Behav
. 2014 Jan;
126:39-49.
PMID: 24382486
Facilitative glucose transporters (GLUT) mediate glucose uptake across the blood-brain-barrier into neurons and glia. Deficits in specific cerebral GLUT isoforms are linked to developmental and neurological dysfunction, but less is...
7.
Greenlee M, Mitzelfelt J, Yu L, Yue Q, Duke B, Harrell C, et al.
Am J Physiol Lung Cell Mol Physiol
. 2013 Oct;
305(11):L878-89.
PMID: 24097558
Female sex predisposes individuals to poorer outcomes during respiratory disorders like cystic fibrosis and influenza-associated pneumonia. A common link between these disorders is dysregulation of alveolar fluid clearance via disruption...
8.
Nemeth C, Harrell C, Beck K, Neigh G
Biol Sex Differ
. 2013 Apr;
4(1):8.
PMID: 23594674
Depression is a common mental disorder that co-occurs in other neurological and somatic diseases. Further, sex differences exist in the prevalence rates of many of these diseases, as well as...
9.
Harrell C, Hardy E, Boss-Williams K, Weiss J, Neigh G
Behav Brain Res
. 2013 Apr;
248:57-61.
PMID: 23583793
Neuropsychiatric disorders often derive from environmental influences that occur at important stages of development and interact with genetics. This study examined the effects of stress during adolescence in rats selectively...
10.
Pyter L, Kelly S, Harrell C, Neigh G
Brain Behav Immun
. 2013 Jan;
30:88-94.
PMID: 23348027
Both basic and clinical research indicates that females are more susceptible to stress-related affective disorders than males. One of the mechanisms by which stress induces depression is via inflammatory signaling...