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Constance Keyserling

Explore the profile of Constance Keyserling including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 218
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Recent Articles
1.
Zheng K, Kaiser Y, van Olden C, Santos R, Dasseux J, Genest J, et al.
Atherosclerosis . 2020 Sep; 311:13-19. PMID: 32919280
Background And Aims: Infusion of high-density lipoprotein (HDL) mimetics failed to induce regression of atherosclerosis in recent randomized clinical trials. However, patients in these previous trials had normal levels of...
2.
Kataoka Y, Andrews J, Duong M, Nguyen T, Schwarz N, Fendler J, et al.
Cardiovasc Diagn Ther . 2017 Jun; 7(3):252-263. PMID: 28567351
Background: CER-001 is an engineered pre-beta high-density lipoprotein (HDL) mimetic, which rapidly mobilizes cholesterol. Infusion of CER-001 3 mg/kg exhibited a potentially favorable effect on plaque burden in the CHI-SQUARE...
3.
Zheng K, van der Valk F, Smits L, Sandberg M, Dasseux J, Baron R, et al.
Atherosclerosis . 2016 Jun; 251:381-388. PMID: 27263077
Background And Aims: Infusion of high-density lipoprotein (HDL) mimetics aimed at reducing atherosclerotic burden has led to equivocal results, which may relate in part to the inability of HDL mimetics...
4.
Tardy C, Goffinet M, Boubekeur N, Cholez G, Ackermann R, Sy G, et al.
PLoS One . 2015 Sep; 10(9):e0137584. PMID: 26335690
Objective: CER-001 is a novel engineered HDL-mimetic comprised of recombinant human apoA-I and charged phospholipids that was designed to mimic the beneficial properties of nascent pre-ß HDL. In this study,...
5.
Tardif J, Ballantyne C, Barter P, Dasseux J, Fayad Z, Guertin M, et al.
Eur Heart J . 2014 May; 35(46):3277-86. PMID: 24780501
Aim: High-density lipoproteins (HDLs) have several potentially protective vascular effects. Most clinical studies of therapies targeting HDL have failed to show benefits vs. placebo. Objective: To investigate the effects of...
6.
Tardy C, Goffinet M, Boubekeur N, Ackermann R, Sy G, Bluteau A, et al.
Atherosclerosis . 2014 Jan; 232(1):110-8. PMID: 24401224
Objective: CER-001 is a novel engineered HDL-mimetic comprised of recombinant human apoA-I and phospholipids that was designed to mimic the beneficial properties of nascent pre-β HDL. In this study, we...