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Conor Chandler

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Articles 7
Citations 34
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Recent Articles
1.
Garcia C, Abrahami D, Polli A, Chu H, Chandler C, Tan M, et al.
Clin Lung Cancer . 2024 Sep; 25(7):634-642. PMID: 39232917
Introduction: The comparative efficacy and safety of lorlatinib, a third-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitor (TKI), versus second-generation ALK TKIs as a first-line treatment for ALK+ advanced/metastatic nonsmall...
2.
Kim T, Girard N, Leighl N, Sabari J, Rahhali N, Schioppa C, et al.
Future Oncol . 2023 Oct; 20(8):447-458. PMID: 37882460
We assessed relative efficacy and safety of amivantamab versus mobocertinib in patients with non-small-cell lung cancer with exon 20 insertion (exon20ins) mutations who progressed on prior platinum-based chemotherapy. This matching-adjusted...
3.
Chandler C, Burnett H, Schaible K, Senthil V, Kato M, Miura Y, et al.
J Med Econ . 2023 Jul; 26(1):1009-1018. PMID: 37505931
Aims: The treatment landscape of renal cell carcinoma has changed with the introduction of targeted therapies. While the clinical benefit of cabozantinib is well-established for Japanese patients who have received...
4.
McGarry L, Bhaiwala Z, Lopez A, Chandler C, Pelligra C, Rubin J, et al.
PLoS One . 2023 Apr; 18(4):e0283479. PMID: 37043485
Objectives: Cystic fibrosis (CF) is a rare genetic disease characterized by life-shortening lung function decline. Ivacaftor, a CF transmembrane conductance regulator modulator (CFTRm), was approved in 2012 for people with...
5.
Chandler C, Folse H, Gal P, Chavan A, Proskorovsky I, Franco-Villalobos C, et al.
J Mark Access Health Policy . 2021 Jun; 9(1):1922163. PMID: 34122780
: Simulation modeling facilitates the estimation of long-term health and economic outcomes to inform healthcare decision-making. : To develop a framework to simulate progression of Parkinson's disease (PD), capturing motor...
6.
Rubin J, OCallaghan L, Pelligra C, Konstan M, Ward A, Ishak J, et al.
Ther Adv Respir Dis . 2019 Feb; 13:1753466618820186. PMID: 30803355
Background: Lumacaftor/ivacaftor combination therapy is efficacious and generally safe for patients with cystic fibrosis (CF) homozygous for the F508del-CF transmembrane conductance regulator (CFTR) mutation. However, long-term survival benefits of lumacaftor/ivacaftor...
7.
Pelligra C, Parikh K, Guo S, Chandler C, Mouro J, Abouzaid S, et al.
Clin Ther . 2017 Oct; 39(10):1986-2005.e5. PMID: 28967482
Purpose: Pomalidomide plus low-dose dexamethasone (POM-d), daratumumab monotherapy (DARA), and carfilzomib monotherapy (CAR) have been approved for use in the treatment of patients with heavily pretreated relapsed-refractory multiple myeloma (RRMM)...