Cong-Jian Xu
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Explore the profile of Cong-Jian Xu including associated specialties, affiliations and a list of published articles.
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52
Citations
521
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Recent Articles
1.
Liu Y, Jiang J, Du S, Mu L, Fan J, Hu J, et al.
Science
. 2024 Jun;
384(6701):eadk5382.
PMID: 38870290
Polycystic ovary syndrome (PCOS), a prevalent reproductive disorder in women of reproductive age, features androgen excess, ovulatory dysfunction, and polycystic ovaries. Despite its high prevalence, specific pharmacologic intervention for PCOS...
2.
Zhang K, Zhang F, Zhang Z, Fang K, Sun W, Kong N, et al.
Protein Cell
. 2024 Jan;
15(7):512-529.
PMID: 38167949
Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility. Inadequate understanding of the ovulation drivers hinders PCOS intervention. Herein, we report that follicle stimulating hormone (FSH) controls follicular...
3.
Du S, Hu L, Zhou B, Zhang Z, Li M, Chang D, et al.
Biochem Biophys Res Commun
. 2023 Oct;
681:225-231.
PMID: 37783121
The commitment of mesenchymal stem cells (MSCs) to preadipocytes and the termination of differentiation to adipocytes are critical for maintaining systemic energy homeostasis. However, our knowledge of the molecular mechanisms...
4.
Jie X, Zhang M, Du M, Cai Q, Cong Q, Xu C, et al.
Transl Cancer Res
. 2022 Sep;
11(8):2636-2646.
PMID: 36093536
Background: Circulating tumor cells (CTCs) have considered to be promising liquid biopsy in cancer due to the intact information of whole cells and the potential to reflect micrometastasis. However, CTCs...
5.
Wang Y, Ren S, Jiang W, Lu J, Zhang X, Li X, et al.
Ann Transl Med
. 2021 Jul;
9(9):788.
PMID: 34268401
Background: CA125 is the most widely used serum marker for preoperative diagnosis of ovarian cancer. However, CA125 elevation is not specific to ovarian cancer. More than 60% of patients who...
6.
Zhao Y, Zhao M, Yang M, Wu T, Xu C, Wang J, et al.
Cancer Res Treat
. 2020 Mar;
52(3):815-829.
PMID: 32138466
Purpose: While numerous epidemiological studies have indicated that omega-3 polyunsaturated fatty acids have anticancer properties in various cancers, the effects and mechanisms of eicosapentaenoic acid (EPA) in ovarian cancer cell...
7.
Zhang M, Cong Q, Zhang X, Zhang M, Lu Y, Xu C
J Cell Physiol
. 2018 Sep;
234(5):6361-6370.
PMID: 30229902
Patients with ovarian cancer frequently develop acquired drug resistance after the long-term chemotherapy, leading to disease progression. Enhanced epithelial-mesenchymal transition (EMT) has been implicated in chemoresistance of ovarian cancer cells;...
8.
Fan D, Zhou W, Jin L, Li M, Xu X, Xu C
Reprod Sci
. 2018 Jun;
26(4):532-542.
PMID: 29909746
Background: Decidual γδ T cells are known to regulate the function of trophoblasts at the maternal-fetal interface; however, little is known about the molecular mechanisms of cross talk between trophoblast...
9.
Zhang M, Hong S, Cai Q, Zhang M, Chen J, Zhang X, et al.
Drug Deliv
. 2018 Mar;
25(1):797-806.
PMID: 29542355
Ovarian cancer is the leading cause of cancer death among gynecological malignancies. The high mortality rate has not been significantly reduced despite advances in surgery and chemotherapy. Gene therapy shows...
10.
Hong S, Zhang M, Zhang M, Yu Y, Chen J, Zhang X, et al.
Drug Deliv
. 2018 Feb;
25(1):576-584.
PMID: 29461120
The distinct hormone molecules and receptors, such as follicle-stimulating hormone receptor (FSHR) in ovarian cancer, provide opportunities for more precisely targeted therapy. We previously developed FSHR-mediated nanoparticles and found that...