Colum D MacKinnon
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Explore the profile of Colum D MacKinnon including associated specialties, affiliations and a list of published articles.
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71
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871
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Recent Articles
1.
Mancini M, McKay J, Cockx H, DCruz N, Esper C, Filtjens B, et al.
J Parkinsons Dis
. 2025 Feb;
:1877718X241301065.
PMID: 39973491
This report summarizes the existing literature on the use of technology for the assessment of freezing of gait (FOG) as well as the use of technology to provide insights into...
2.
Lecy E, Linn-Evans M, Amundsen-Huffmaster S, Palnitkar T, Patriat R, Chung J, et al.
J Neurophysiol
. 2024 Aug;
132(3):953-967.
PMID: 39110516
Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) can markedly reduce muscle rigidity in people with Parkinson's disease (PD); however, the mechanisms mediating this effect...
3.
Shemmell J, Falling C, MacKinnon C, Stapley P, Ribeiro D, Stinear J
J Neurophysiol
. 2024 May;
131(6):1299-1310.
PMID: 38691532
Although recent studies in nonhuman primates have provided evidence that transcranial magnetic stimulation (TMS) activates cells within the reticular formation, it remains unclear whether descending brain stem projections contribute to...
4.
Verma A, Nandakumar B, Acedillo K, Yu Y, Marshall E, Schneck D, et al.
Front Neurosci
. 2024 Mar;
18:1338624.
PMID: 38449736
Increasing evidence suggests slow-wave sleep (SWS) dysfunction in Parkinson's disease (PD) is associated with faster disease progression, cognitive impairment, and excessive daytime sleepiness. Beta oscillations (8-35 Hz) in the basal...
5.
Verma A, Nandakumar B, Acedillo K, Yu Y, Marshall E, Schneck D, et al.
bioRxiv
. 2023 Nov;
PMID: 37961389
Increasing evidence associates slow-wave sleep (SWS) dysfunction with neurodegeneration. Using a within-subject design in the nonhuman primate model of Parkinson's disease (PD), we found that reduced SWS quantity in mild...
6.
Zapata Amaya V, Aman J, Johnson L, Wang J, Patriat R, Hill M, et al.
Front Hum Neurosci
. 2023 Oct;
17:1178527.
PMID: 37810764
Introduction: Evidence suggests that beta band (11-35 Hz) oscillations in the basal ganglia thalamocortical (BGTC) circuit are linked to Parkinson's disease (PD) pathophysiology. Previous studies on neural responses in the...
7.
Zadeh A, Videnovic A, MacKinnon C, Alibiglou L
Clin Neurophysiol
. 2023 Jan;
146:97-108.
PMID: 36608531
Objective: Freezing of gait (FOG) in Parkinson's disease (PD) is characterized by the inability to initiate stepping, despite the intention to do so. This study used a startling acoustic stimulus...
8.
Verma A, Yu Y, Acosta-Lenis S, Havel T, Escobar Sanabria D, Molnar G, et al.
Neurobiol Dis
. 2022 Dec;
176:105963.
PMID: 36521781
Excessive daytime sleepiness is a recognized non-motor symptom that adversely impacts the quality of life of people with Parkinson's disease (PD), yet effective treatment options remain limited. Deep brain stimulation...
9.
Lu C, Louie K, Stutz A, MacKinnon C, Cooper S
J Neurol
. 2022 Sep;
270(1):386-393.
PMID: 36100730
Objective: This experiment tested if balance performance differed between a standardized treadmill surface perturbation task and a clinical pull test and was affected by medication or the presence of body...
10.
Verma A, Acosta Lenis S, Aman J, Escobar Sanabria D, Wang J, Pearson A, et al.
NPJ Parkinsons Dis
. 2022 Sep;
8(1):116.
PMID: 36097027
To elucidate the role of the basal ganglia during REM sleep movements in Parkinson's disease (PD) we recorded pallidal neural activity from four PD patients. Unlike desynchronization commonly observed during...