Colm OhUigin
Overview
Explore the profile of Colm OhUigin including associated specialties, affiliations and a list of published articles.
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33
Citations
2211
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Recent Articles
1.
Viard M, OhUigin C, Yuki Y, Bashirova A, Collins D, Urbach J, et al.
Science
. 2024 Jan;
383(6680):319-325.
PMID: 38236978
Heterozygosity of () class I genes is linked to beneficial outcomes after HIV infection, presumably through greater breadth of HIV epitope presentation and cytotoxic T cell response. Distinct allotype pairs,...
2.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh W, Gong W, et al.
Gut Pathog
. 2023 Dec;
15(1):60.
PMID: 38037170
No abstract available.
3.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh W, Gong W, et al.
Gut Pathog
. 2023 Jun;
15(1):28.
PMID: 37322488
Background: Formyl peptide receptor 2 (Fpr2) plays a crucial role in colon homeostasis and microbiota balance. Commensal E. coli is known to promote the regeneration of damaged colon epithelial cells....
4.
Bashirova A, Kasprzak W, OhUigin C, Carrington M
Immunogenetics
. 2022 Nov;
75(3):263-267.
PMID: 36449053
The leukocyte immunoglobulin-like receptor (LILR)B3 and LILRA6 genes encode homologous myeloid inhibitory and activating orphan receptors, respectively. Both genes exhibit a strikingly high level of polymorphism at the amino acid...
5.
Bashirova A, Zheng W, Akdag M, Augusto D, Vince N, Dong K, et al.
Genes Immun
. 2021 Dec;
22(7-8):327-334.
PMID: 34864821
Human immunoglobulin G (IgG) molecules, IgG1, IgG2 and IgG3, exhibit substantial inter-individual variation in their constant heavy chain regions, as discovered by serological methods. This polymorphism is encoded by the...
6.
Liang W, Peng X, Li Q, Wang P, Lv P, Song Q, et al.
Nat Commun
. 2020 Nov;
11(1):5912.
PMID: 33219235
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule,...
7.
Chen K, Yoshimura T, Yao X, Gong W, Huang J, Dzutsev A, et al.
J Pathol
. 2020 Oct;
253(3):339-350.
PMID: 33104252
The cathelin-related antimicrobial peptide CRAMP protects the mouse colon from inflammation, inflammation-associated carcinogenesis, and disrupted microbiome balance, as shown in systemic Cnlp mice (also known as Camp mice). However, the...
8.
Bashirova A, Viard M, Naranbhai V, Grifoni A, Garcia-Beltran W, Akdag M, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(45):28232-28238.
PMID: 33097667
Human leukocyte antigen (HLA) class I allotypes vary in their ability to present peptides in the absence of tapasin, an essential component of the peptide loading complex. We quantified tapasin...
9.
Musich T, Thovarai V, Venzon D, Mohanram V, Tuero I, Miller-Novak L, et al.
J Virol
. 2020 Sep;
94(24).
PMID: 32967951
An efficacious human immunodeficiency virus (HIV) vaccine will likely require induction of both mucosal and systemic immune responses. We compared the immunogenicity and protective efficacy of two mucosal/systemic vaccine regimens...
10.
Savage S, Viard M, OhUigin C, Zhou W, Yeager M, Li S, et al.
Am J Hum Genet
. 2020 Feb;
106(2):264-271.
PMID: 32004448
Severe aplastic anemia (SAA) is a rare disorder characterized by hypoplastic bone marrow and progressive pancytopenia. The etiology of acquired SAA is not understood but is likely related to abnormal...