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Colleen Mockbee

Explore the profile of Colleen Mockbee including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 115
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Recent Articles
1.
Hsiehchen D, Beg M, Kainthla R, Lohrey J, Kazmi S, Khosama L, et al.
Nat Commun . 2024 Mar; 15(1):2178. PMID: 38467639
Immune checkpoint inhibitors targeting PD-1/L1 have modest efficacy in hepatocellular carcinoma as single agents. Targeting membranous phosphatidylserine may induce pro-inflammatory and -immune stimulating effects that enhance immunotherapy activity. This hypothesis...
2.
Fu S, Corr B, Culm-Merdek K, Mockbee C, Youssoufian H, Stagg R, et al.
J Clin Oncol . 2022 Apr; 40(23):2568-2577. PMID: 35439029
Purpose: This phase Ib study evaluated the safety and efficacy of paclitaxel plus navicixizumab, a bispecific antiangiogenic antibody to vascular endothelial growth factor and delta-like ligand 4, against platinum-resistant ovarian...
3.
Clayton N, Khan-Malek R, Dangler C, Zhang D, Ascah A, Gains M, et al.
Radiat Res . 2020 Dec; 195(2):191-199. PMID: 33302291
Exposure to acute, high-dose, whole-body ionizing radiation results in bone marrow failure (hematopoietic acute radiation syndrome with resultant infection, bleeding, anemia, and increased risk of death). Sargramostim (yeast-derived rhu GM-CSF),...
4.
Zhong Y, Pouliot M, Downey A, Mockbee C, Roychowdhury D, Wierzbicki W, et al.
Int J Radiat Biol . 2020 Sep; 97(sup1):S100-S116. PMID: 32960660
Background: High dose ionizing radiation exposure is associated with myelo-depression leading to pancytopenia and the expected clinical manifestations of acute radiation syndrome (ARS). Herein, we evaluated the efficacy of sargramostim...
5.
Leary R, Gardner R, Mockbee C, Roychowdhury D
Cureus . 2019 Jun; 11(3):e4276. PMID: 31157137
Drug development in oncology today routinely focuses on approaches that utilize the patients' immune system to destroy the malignancy. Combinatorial approaches of antineoplastic agents, both new and old, are being...
6.
OBrien N, Conklin D, Beckmann R, Luo T, Chau K, Thomas J, et al.
Mol Cancer Ther . 2018 Feb; 17(5):897-907. PMID: 29483214
The cyclinD:CDK4/6:Rb axis is dysregulated in a variety of human cancers. Targeting this pathway has proven to be a successful therapeutic approach in ER breast cancer. In this study, and...
7.
Melemed A, Mockbee C, Orlando M
J Clin Oncol . 2005 Nov; 23(31):8139-40. PMID: 16258122
No abstract available.