Colin McLean
Overview
Explore the profile of Colin McLean including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
169
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0
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Recent Articles
1.
Candela M, Addison M, Aird R, Man T, Cartwright J, Ashmore-Harris C, et al.
NPJ Regen Med
. 2025 Jan;
10(1):5.
PMID: 39843512
Acute liver failure is a rapidly progressing, life-threatening condition most commonly caused by an overdose of acetaminophen (paracetamol). The antidote, N-acetylcysteine (NAC), has limited efficacy when liver injury is established....
2.
Cooper R, Sutherland C, Smith L, Cowan G, Barnett M, Mitchell D, et al.
Front Immunol
. 2024 Jul;
15:1412211.
PMID: 39011042
Adoptive immunotherapy with Epstein-Barr virus (EBV)-specific T cells is an effective treatment for relapsed or refractory EBV-induced post-transplant lymphoproliferative disorders (PTLD) with overall survival rates of up to 69%. EBV-specific...
3.
McLean C, Sorokin A, Armstrong J, Sorokina O
Curr Protoc
. 2023 Dec;
3(12):e940.
PMID: 38050642
In a living cell, proteins interact to assemble both transient and constant molecular complexes, which transfer signals/information around internal pathways. Modern proteomic techniques can identify the constituent components of these...
4.
McLean C, Sorokin A, Simpson T, Armstrong J, Sorokina O
Bioinform Adv
. 2023 Oct;
3(1):vbad137.
PMID: 37860105
Motivation: Biological function in protein complexes emerges from more than just the sum of their parts: molecules interact in a range of different sub-complexes and transfer signals/information around internal pathways....
5.
McLean C, Capurro D
AMIA Annu Symp Proc
. 2023 May;
2022:746-755.
PMID: 37128394
: Clinical guidelines recommend best care pathways for many clinical conditions. When significant data from clinical trials become available, new clinical guidelines are published, formalizing the advances in the field....
6.
Sorokina O, McLean C, Croning M, Heil K, Wysocka E, He X, et al.
Sci Rep
. 2021 Aug;
11(1):16240.
PMID: 34349214
No abstract available.
7.
Sorokina O, McLean C, Croning M, Heil K, Wysocka E, He X, et al.
Sci Rep
. 2021 May;
11(1):9967.
PMID: 33976238
Genes encoding synaptic proteins are highly associated with neuronal disorders many of which show clinical co-morbidity. We integrated 58 published synaptic proteomic datasets that describe over 8000 proteins and combined...
8.
McLean C, McMillan L, Petrik J, Fraser A, Morrison A
Vox Sang
. 2020 Sep;
115(8):676-685.
PMID: 32966615
Background: Cryopreserved platelets are generally produced and stored in plasma. With the advent of additive solutions being routinely used it would be prudent to examine producing and storing these units...
9.
Kanellopoulos A, Mariano V, Spinazzi M, Woo Y, McLean C, Pech U, et al.
Cell
. 2020 Mar;
180(6):1178-1197.e20.
PMID: 32200800
Social impairment is frequently associated with mitochondrial dysfunction and altered neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it remains unknown whether mitochondrial disruption contributes to social behavioral deficits....
10.
Chapelle J, Sorokina O, McLean C, Salemme V, Alfieri A, Angelini C, et al.
Front Cell Dev Biol
. 2019 Nov;
7:222.
PMID: 31681758
The p140Cap adaptor protein is a scaffold molecule physiologically expressed in few epithelial tissues, such as the mammary gland, and in differentiated neurons. While the role of p140Cap in mammary...