Colin A Hodgkinson
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Explore the profile of Colin A Hodgkinson including associated specialties, affiliations and a list of published articles.
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78
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2384
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Recent Articles
11.
Lohoff F, Roy A, Jung J, Longley M, Rosoff D, Luo A, et al.
Mol Psychiatry
. 2020 May;
26(6):2224-2237.
PMID: 32398718
Alcohol use disorder (AUD) is a chronic debilitating disorder with limited treatment options and poorly defined pathophysiology. There are substantial genetic and epigenetic components; however, the underlying mechanisms contributing to...
12.
Wiers C, De Carvalho L, Hodgkinson C, Schwandt M, Kim S, Diazgranados N, et al.
Addict Biol
. 2019 Nov;
26(1):e12838.
PMID: 31713961
The translocator protein (TSPO) transports cholesterol into mitochondria and is involved in steroidogenesis. The TSPO polymorphism rs6971 influences binding of cholesterol and other TSPO ligands including positron-emission tomography (PET) imaging...
13.
Luo A, Jung J, Longley M, Rosoff D, Charlet K, Muench C, et al.
Neuropsychopharmacology
. 2019 Aug;
45(2):327-336.
PMID: 31466081
To investigate the potential role of alcohol use disorder (AUD) in aging processes, we employed Levine's epigenetic clock (DNAm PhenoAge) to estimate DNA methylation age in 331 individuals with AUD...
14.
Bowers M, Buzzell G, Salo V, Troller-Renfree S, Hodgkinson C, Goldman D, et al.
Dev Psychobiol
. 2019 Aug;
62(2):181-190.
PMID: 31372986
The Val158Met rs4680 single-nucleotide polymorphism (SNP) at the catechol-O-methyltransferase (COMT) gene, primarily involved in dopamine breakdown within prefrontal cortex, has shown relations with inhibitory control (IC) in both adults and...
15.
Lovallo W, Acheson A, Cohoon A, Sorocco K, Vincent A, Hodgkinson C, et al.
PLoS One
. 2019 Jun;
14(6):e0218212.
PMID: 31185043
Early life adversity (ELA) negatively affects health behaviors in adulthood, but pathways from ELA exposure to behavioral outcomes are poorly understood. ELA in childhood and adolescence may translate into adult...
16.
Zhou Z, Blandino P, Yuan Q, Shen P, Hodgkinson C, Virkkunen M, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(26):13107-13115.
PMID: 31182603
Artificially selected model organisms can reveal hidden features of the genetic architecture of the complex disorders that they model. Addictions are disease phenotypes caused by different intermediate phenotypes and pathways...
17.
Lovallo W, Cohoon A, Sorocco K, Vincent A, Acheson A, Hodgkinson C, et al.
Alcohol Clin Exp Res
. 2019 Jun;
43(7):1519-1527.
PMID: 31150143
Background: Risk for alcoholism may be enhanced by exposure to early-life adversity (ELA) in persons with genetic vulnerabilities. We examined ELA in the presence of a common variant of the...
18.
Kano S, Hodgkinson C, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, et al.
Mol Psychiatry
. 2018 Aug;
25(1):194-205.
PMID: 30127472
Clinical studies frequently report that patients with major mental illness such as schizophrenia and bipolar disorder have co-morbid physical conditions, suggesting that systemic alterations affecting both brain and peripheral tissues...
19.
Landefeld C, Hodgkinson C, Spagnolo P, Marietta C, Shen P, Sun H, et al.
Transl Psychiatry
. 2018 Mar;
8(1):72.
PMID: 29581423
Genome-wide association studies (GWAS) of complex, heritable, behavioral phenotypes have yielded an incomplete accounting of the genetic influences. The identified loci explain only a portion of the observed heritability, and...
20.
Suchankova P, Yan J, Schwandt M, Stangl B, Jerlhag E, Engel J, et al.
Alcohol Alcohol
. 2017 May;
52(4):425-430.
PMID: 28481975
Aims: The orexigenic peptide ghrelin may enhance the incentive value of food-, drug- and alcohol-related rewards. Consistent with preclinical findings, human studies indicate a role of ghrelin in alcohol use...