Colette M Knight
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Explore the profile of Colette M Knight including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
186
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Recent Articles
1.
Zhao Y, Knight C, Jiang Z, Delgado E, Van Hoven A, Ghanny S, et al.
Autoimmun Rev
. 2022 Feb;
21(5):103058.
PMID: 35108619
Type 1 diabetes (T1D) is an autoimmune disease that causes a deficit of pancreatic islet β cells. Millions of individuals worldwide have T1D, and its incidence increases annually. Recent clinical...
2.
Knight C, Gutierrez-Juarez R, Lam T, Arrieta-Cruz I, Huang L, Schwartz G, et al.
Diabetes
. 2017 Nov;
66(12):3143-3144.
PMID: 29162736
No abstract available.
3.
Qiang L, Kon N, Zhao W, Jiang L, Knight C, Welch C, et al.
Cell Rep
. 2015 Jun;
11(11):1797-808.
PMID: 26074075
Obesity is associated with higher incidence of cancer, but the predisposing mechanisms remain poorly understood. The NAD(+)-dependent deacetylase SirT1 orchestrates metabolism, cellular survival, and growth. However, there is no unifying...
4.
Arrieta-Cruz I, Knight C, Gutierrez-Juarez R
J Alzheimers Dis
. 2015 Apr;
46(4):843-8.
PMID: 25869787
Patients with Alzheimer's disease (AD) have a higher risk for developing insulin resistance and diabetes. Amyloid plaques, a hallmark of AD, are composed of amyloid-β (Aβ). Because the mediobasal hypothalamus...
5.
Haeusler R, Hartil K, Vaitheesvaran B, Arrieta-Cruz I, Knight C, Cook J, et al.
Nat Commun
. 2014 Oct;
5:5190.
PMID: 25307742
Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former are low and the latter are exaggerated,...
6.
Arrieta-Cruz I, Su Y, Knight C, Lam T, Gutierrez-Juarez R
Diabetes
. 2013 Jan;
62(4):1152-8.
PMID: 23274895
The metabolism of lactate to pyruvate in the mediobasal hypothalamus (MBH) regulates hepatic glucose production. Because astrocytes and neurons are functionally linked by metabolic coupling through lactate transfer via the...
7.
Knight C, Gutierrez-Juarez R, Lam T, Arrieta-Cruz I, Huang L, Schwartz G, et al.
Diabetes
. 2011 Sep;
60(11):2691-700.
PMID: 21896928
Objective: Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabolic processes. We investigate the site of resveratrol action on glucose metabolism and the contribution of...