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Cleo Derichs

Explore the profile of Cleo Derichs including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 17
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Recent Articles
1.
van Dijk M, Ruiter T, van der Veen S, Rab M, van Oirschot B, Bos J, et al.
Hemasphere . 2024 Jun; 8(6):e109. PMID: 38919958
Mitapivat is an investigational, oral, small-molecule allosteric activator of pyruvate kinase (PK). PK is a regulatory glycolytic enzyme that is key in providing the red blood cell (RBC) with sufficient...
2.
van Dijk M, Rab M, van Oirschot B, Bos J, Derichs C, Rijneveld A, et al.
Blood Adv . 2023 Nov; 7(24):7539-7550. PMID: 37934880
Targeting the primary pathogenic event of sickle cell disease (SCD), the polymerization of sickle hemoglobin (HbS), may prevent downstream clinical events. Mitapivat, an oral pyruvate kinase (PK) activator, has therapeutic...
3.
van Dijk M, Rab M, van Oirschot B, Bos J, Derichs C, Rijneveld A, et al.
Am J Hematol . 2022 Apr; 97(7):E226-E229. PMID: 35384026
No abstract available.