Clayton Mansel
Overview
Explore the profile of Clayton Mansel including associated specialties, affiliations and a list of published articles.
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7
Citations
54
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Recent Articles
1.
Distinct medical and substance use histories associate with cognitive decline in Alzheimer's Disease
Mansel C, Mazzotti D, Townley R, Sardiu M, Swerdlow R, Honea R, et al.
medRxiv
. 2024 Dec;
PMID: 39649607
Introduction: Phenotype clustering reduces patient heterogeneity and could be useful when designing precision clinical trials. We hypothesized that the onset of early cognitive decline in patients would exhibit variance predicated...
2.
Gabrielli A, Novikova L, Ranjan A, Wang X, Ernst N, Abeykoon D, et al.
Alzheimers Dement
. 2024 Oct;
20(12):8429-8443.
PMID: 39441557
Introduction: Alzheimer's disease (AD) features changes in mitochondrial structure and function. Investigators debate where to position mitochondrial pathology within the chronology and context of other AD features. Methods: To address...
3.
Gratuze M, Schlachetzki J, DOliveira Albanus R, Jain N, Novotny B, Brase L, et al.
Neuron
. 2022 Nov;
111(2):202-219.e7.
PMID: 36368315
In addition to tau and Aβ pathologies, inflammation plays an important role in Alzheimer's disease (AD). Variants in APOE and TREM2 increase AD risk. ApoE4 exacerbates tau-linked neurodegeneration and inflammation...
4.
Troutwine B, Strope T, Franczak E, Lysaker C, Hamid L, Mansel C, et al.
Neurobiol Dis
. 2022 Jun;
171:105781.
PMID: 35667615
Introduction: Mitochondrial dysfunction is observed in Alzheimer's disease (AD). However, the relationship between functional mitochondrial deficits and AD pathologies is not well established in human subjects. Methods: Post-mortem human brain...
5.
Fross S, Mansel C, McCormick M, Vohra B
Toxicol Sci
. 2021 Jan;
180(2):342-355.
PMID: 33481012
Tributyltin (TBT) remains a global health concern. The primary route of human exposure to TBT is either through ingestion or skin absorption, but TBT's effects on the peripheral nervous system...
6.
Mansel C, Fross S, Rose J, Dema E, Mann A, Hart H, et al.
Neurotoxicol Teratol
. 2019 Feb;
72:58-70.
PMID: 30776472
Lead (Pb) is a teratogen that poses health risks after acute and chronic exposure. Lead is deposited in the bones of adults and is continuously leached into the blood for...
7.
Pottorf T, Mann A, Fross S, Mansel C, Vohra B
Neurochem Int
. 2018 Oct;
121:86-97.
PMID: 30278188
Golgi fragmentation and loss of Nicotinamide Mononucleotide Adenylyltransferase 2 (NMNAT2) are the early key features of many neurodegenerative disorders. We investigated the link between NMNAT2 loss, Golgi fragmentation and axon...