Claus P Schmitt
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Explore the profile of Claus P Schmitt including associated specialties, affiliations and a list of published articles.
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42
Citations
576
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Recent Articles
1.
Kuper K, Poschet G, Rossmann J, Garbade S, Spiegelhalter A, Wen D, et al.
Amino Acids
. 2024 Dec;
57(1):2.
PMID: 39673003
Dipeptides (DPs), composed of two amino acids (AAs), hold significant therapeutic potential but remain underexplored. Given the crucial role of AAs in central nervous system (CNS) function, this study investigated...
2.
Bernardor J, Flammier S, Zagozdzon I, Lalayiannis A, Koster-Kamphuis L, Verrina E, et al.
Kidney Int Rep
. 2024 Jul;
9(7):2096-2109.
PMID: 39081774
Introduction: Secondary hyperparathyroidism (sHPT) is particularly severe in rapidly growing infants in dialysis. Although cinacalcet is effective and licensed in dialysis in children aged >3 years, its efficacy and safety...
3.
Borzych-Duzalka D, Shroff R, Ranchin B, Zhai Y, Paglialonga F, Kari J, et al.
Kidney Int Rep
. 2024 Jun;
9(6):1694-1704.
PMID: 38899176
Introduction: Fluid and salt overload in patients on dialysis result in high blood pressure (BP), left ventricular hypertrophy (LVH) and hemodynamic instability, resulting in cardiovascular morbidity. Methods: Analysis of 910...
4.
Pfeffer T, Krug S, Kracke T, Schurfeld R, Colbatzky F, Kirschner P, et al.
Acta Physiol (Oxf)
. 2024 Mar;
240(4):e14126.
PMID: 38517248
Aim: Although of potential biomedical relevance, dipeptide metabolism has hardly been studied. We found the dipeptidase carnosinase-2 (CN2) to be abundant in human proximal tubules, which regulate water and solute...
5.
Martin-Higueras C, Borghese L, Torres A, Fraga-Bilbao F, Santana-Estupinan R, Stefanidis C, et al.
Kidney Int Rep
. 2024 Feb;
9(1):114-133.
PMID: 38312792
Introduction: The RNA interference (RNAi) medication lumasiran reduces hepatic oxalate production in primary hyperoxaluria type 1 (PH1). Data outside clinical trials are scarce. Methods: We report on retrospectively and observationally...
6.
Balzer M, Rong S, Nordlohne J, Zemtsovski J, Schmidt S, Stapel B, et al.
Biomolecules
. 2020 Nov;
10(11).
PMID: 33228017
Peritoneal dialysis (PD) is limited by glucose-mediated peritoneal membrane (PM) fibrosis, angiogenesis, and ultrafiltration failure. Influencing PM integrity by pharmacologically targeting sodium-dependent glucose transporter (SGLT)-mediated glucose uptake has not been...
7.
Taylan C, Driemeyer J, Schmitt C, Pape L, Buscher R, Galiano M, et al.
Am J Cardiol
. 2020 Sep;
136:38-48.
PMID: 32946862
Twenty-four patients with bi-allelic familial hypercholesterolemia commencing chronic lipoprotein apheresis (LA) at a mean age of 8.5 ± 3.1 years were analysed retrospectively and in part prospectively with a mean...
8.
Shroff R, Fewtrell M, Heuser A, Kolevica A, Lalayiannis A, McAlister L, et al.
J Bone Miner Res
. 2020 Aug;
36(1):133-142.
PMID: 32786145
Serum calcium (Ca), bone biomarkers, and radiological imaging do not allow accurate evaluation of bone mineral balance (BMB), a key determinant of bone mineral density (BMD) and fracture risk. We...
9.
Weigand T, Pfeffer T, Garbade S, Klingbeil K, Colbatzky F, Becker M, et al.
Int J Mol Sci
. 2020 Jul;
21(14).
PMID: 32664451
Carnosinase 1 (CN1) is encoded by the gene and degrades carnosine and anserine, two natural histidine-containing dipeptides. In vitro and in vivo studies suggest carnosine- and anserine-mediated protection against long-term...
10.
Luirink I, Hutten B, Greber-Platzer S, Kolovou G, Dann E, de Ferranti S, et al.
Atherosclerosis
. 2020 Mar;
299:24-31.
PMID: 32199148
Background And Aims: Homozygous familial hypercholesterolemia (hoFH) may cause life-threatening atherosclerotic cardiovascular disease in childhood. Lipoprotein apheresis (LA) is considered a pivotal treatment option, but data on its efficacy, safety...