Claudia van Alfen
Overview
Explore the profile of Claudia van Alfen including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
42
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0
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Recent Articles
1.
Kuper W, van Alfen C, van Eck L, de Man S, Willemsen M, van Gassen K, et al.
JIMD Rep
. 2020 Mar;
52(1):23-27.
PMID: 32154056
Background: CLN3 disease is a disorder of lysosomal homeostasis predominantly affecting the retina and the brain. The severity of the underlying mutations in particularly determines onset and course of neurological...
2.
Kuper W, van Alfen C, van Eck L, Huijgen B, Nieuwenhuis E, van Brussel M, et al.
Neurology
. 2019 Jun;
93(3):e293-e297.
PMID: 31182507
Objective: To delineate timing of motor decline in CLN3 disease. Methods: Motor function, assessed by the 6-Minute Walk Test (6MWT), was evaluated repeatedly in 15 patients with CLN3 disease, resulting...
3.
Kuper W, van Alfen C, Rigterink R, Fuchs S, van Genderen M, van Hasselt P
J Inherit Metab Dis
. 2018 Feb;
41(2):257-261.
PMID: 29392585
Background: CLN3 disease is a major cause of childhood neurodegeneration. Onset of visual failure around 6 years of age is thought to precede cognitive deterioration by a few years, but...
4.
Kuper W, van Alfen C, van Eck L, van den Broek B, Huisman A, van Genderen M, et al.
JAMA Ophthalmol
. 2017 Oct;
135(12):1451-1453.
PMID: 29049447
No abstract available.
5.
Olsman E, Veneberg B, van Alfen C, Touwen D
Nurs Ethics
. 2017 Apr;
26(1):50-60.
PMID: 28438074
Background:: Metaphors are often used within the context of ethics and healthcare but have hardly been explored in relation to moral reasoning. Objective:: To describe a central set of metaphors...