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Claudia Fecher-Trost

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Articles 45
Citations 556
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Recent Articles
1.
Gehl A, Klawitter D, Wissenbach U, Cole M, Wesely C, Lohr H, et al.
Reprod Biol Endocrinol . 2025 Mar; 23(1):33. PMID: 40038668
Background: The syncytiotrophoblast (STB) layer of the placenta is formed by cell fusion of cytotrophoblasts, acts as a feto-maternal barrier, is required for the production of pregnancy hormones such as...
2.
Oz S, Keren-Raifman T, Sharon T, Subramaniam S, Pallien T, Katz M, et al.
BMC Biol . 2024 Nov; 22(1):276. PMID: 39609812
Background: The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated Ca1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenergic receptors (βAR) activates protein...
3.
Vollmer A, Fecher-Trost C, Bever C, Tam C, Wagmann L, Meyer M
Sci Rep . 2024 Sep; 14(1):21397. PMID: 39271810
Analysis of amatoxins is of great importance as these cyclic peptides contribute to a high number of fatalities each year. Development of analytical approaches needs to focus on rapid, sensitive,...
4.
Martus D, Williams S, Pichi K, Mannebach-Gotz S, Kaiser N, Wardas B, et al.
Arterioscler Thromb Vasc Biol . 2024 Jul; 44(8):1833-1851. PMID: 38957986
Background: Tight control of cytoplasmic Ca concentration in endothelial cells is essential for the regulation of endothelial barrier function. Here, we investigated the role of Cavβ3, a subunit of voltage-gated...
5.
Hart M, Kern F, Fecher-Trost C, Krammes L, Aparicio E, Engel A, et al.
Exp Mol Med . 2024 Mar; 56(4):935-945. PMID: 38556547
The identification of targetomes remains a challenge given the pleiotropic effect of miRNAs, the limited effects of miRNAs on individual targets, and the sheer number of estimated miRNA-target gene interactions...
6.
Stachon T, Fecher-Trost C, Latta L, Yapar D, Fries F, Meyer M, et al.
Acta Ophthalmol . 2023 Dec; 102(4):e635-e645. PMID: 38130099
Purpose: Congenital aniridia is a rare disease, which is in most cases related to PAX6 haploinsufficiency. Aniridia associated keratopathy (AAK) also belongs to ocular signs of congenital aniridia. In AAK,...
7.
Gotz V, Qiao S, Das D, Wartenberg P, Wyatt A, Wahl V, et al.
Cell Rep . 2023 May; 42(6):112543. PMID: 37224016
Gonadotropes in the anterior pituitary gland are essential for fertility and provide a functional link between the brain and the gonads. To trigger ovulation, gonadotrope cells release massive amounts of...
8.
Diener C, Hart M, Fecher-Trost C, Knittel J, Rheinheimer S, Meyer M, et al.
Cell Mol Biol Lett . 2023 Jan; 28(1):8. PMID: 36694129
Among the concepts in biology that are widely taken granted is a potentiated cooperative effect of multiple miRNAs on the same target. This strong hypothesis contrasts insufficient experimental evidence. The...
9.
Wartenberg P, Lux F, Busch K, Fecher-Trost C, Wyatt A, Flockerzi V, et al.
MethodsX . 2022 Dec; 9:101604. PMID: 36569450
Transient receptor potential (TRP) ion channels play important roles in fundamental biological processes throughout the body of humans and mice. TRP channel dysfunction manifests in different disease states, therefore, these...
10.
Kogel A, Fecher-Trost C, Wissenbach U, Flockerzi V, Schaefer M
Cell Calcium . 2022 Aug; 106:102634. PMID: 35917684
Amongst the superfamily of transient receptor potential (TRP) channels, TRPV5 and TRPV6 are specialized members that mediate Ca-selective transport across epithelial membranes. Intriguingly, fluorescent fusion proteins of TRPV5 or TRPV6...