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Clarissa Menezes Maya-Monteiro

Explore the profile of Clarissa Menezes Maya-Monteiro including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 197
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Recent Articles
1.
Salum K, Assis I, Kopke U, Palhinha L, Abreu G, Gouvea L, et al.
Diabetes Metab Syndr Obes . 2025 Feb; 18:283-303. PMID: 39906696
Purpose: Obesity is a complex disease caused by a combination of genetic, environmental, and epigenetic factors, and is associated with an increased risk of chronic diseases. The leptin-melanocortin pathway integrates...
2.
Assis I, Salum K, Felicio R, Palhinha L, Abreu G, Silva T, et al.
Front Endocrinol (Lausanne) . 2025 Feb; 15:1495534. PMID: 39897959
Introduction: Genetic obesity is considered a rare disease, affecting up to 10% of patients with severe early-onset obesity. Over the past years, significant advances have been made; however, the majority...
3.
Proenca da Fonseca A, Assis I, Salum K, Palhinha L, Abreu G, Zembrzuski V, et al.
Front Genet . 2024 Jun; 15:1363417. PMID: 38841722
Introduction: Obesity is a multifactorial disease associated with the development of many comorbidities. This disease is associated with several metabolic alterations; however, it has been shown that some individuals with...
4.
Proenca da Fonseca A, Assis I, Salum K, Palhinha L, Abreu G, Zembrzuski V, et al.
Eat Weight Disord . 2022 Nov; 27(8):3665-3674. PMID: 36436143
Purpose: SH2B1 gene encodes an important adaptor protein to receptor tyrosine kinases or cytokine receptors associated with Janus kinases. This gene has been associated with the structural and functional modulation...
5.
Salum K, Rolando J, Zembrzuski V, Carneiro J, Mello C, Maya-Monteiro C, et al.
Front Endocrinol (Lausanne) . 2021 Sep; 12:722441. PMID: 34504472
Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition to obesogenic environmental factors combined with genetic susceptibility. In the past two decades, advances in genetic research...
6.
Proenca da Fonseca A, Abreu G, Palhinha L, Zembrzuski V, Junior M, Carneiro J, et al.
Diabetes Metab Syndr Obes . 2021 Jan; 14:11-22. PMID: 33442278
Background: Brain-derived neurotrophic factor (BDNF) is a pro-survival factor in the brain that also regulates energy balance. loss-of-function point mutations are responsible for haploinsufficiency, causing severe early-onset obesity. Up to...
7.
Salum K, de Souza G, Abreu G, Junior M, Kohlrausch F, Carneiro J, et al.
Front Genet . 2020 Dec; 11:608840. PMID: 33362866
Background: The melanocortinergic pathway orchestrates the energy homeostasis and impairments in this system often lead to an increase in body weight. Rare variants in the () gene resulting in partial...
8.
Souza-Almeida G, Palhinha L, Liechocki S, Aparecida da Silva Pereira J, Reis P, Dib P, et al.
J Leukoc Biol . 2020 Oct; 109(6):1131-1138. PMID: 33070353
Leptin is a pleiotropic adipokine that regulates immunometabolism centrally and peripherally. Obese individuals present increased levels of leptin in the blood and develop hypothalamic resistance to this adipokine. Here we...
9.
Maya-Monteiro C, Correa-da-Silva F, Hofmann S, Hesselink M, la Fleur S, Yi C
Neuroendocrinology . 2020 May; 111(3):263-272. PMID: 32422642
Background: In peripheral tissues, the lipid droplet (LD) organelle links lipid metabolism, inflammation, and insulin resistance. Little is known about the brain LDs. Objectives: We hypothesized that hypothalamic LDs would...
10.
Palhinha L, Liechocki S, Hottz E, Aparecida da Silva Pereira J, de Almeida C, Moraes-Vieira P, et al.
Front Endocrinol (Lausanne) . 2020 Jan; 10:841. PMID: 31920961
Leptin is an adipokine with well-known effects on the central nervous system including the induction of energy expenditure and satiety. Leptin also has major relevance when activating immune cells and...