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Clara P Manrique

Explore the profile of Clara P Manrique including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 797
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Recent Articles
1.
Beecham A, Amezcua L, Chinea A, Manrique C, Gomez L, Martinez A, et al.
PLoS One . 2022 Dec; 17(12):e0279132. PMID: 36548255
The Major Histocompatibility Complex (MHC) makes the largest genetic contribution to multiple sclerosis (MS) susceptibility, with 32 independent effects across the region explaining 20% of the heritability in European populations....
2.
Chiong-Rivero H, Robers M, Martinez A, Manrique C, Diaz A, Polito K, et al.
Mult Scler J Exp Transl Clin . 2021 Mar; 7(1):2055217321995947. PMID: 33717502
Background: Health communication tools like film are capable of reducing health disparities and could be effective in addressing negative illness perceptions of MS in Hispanics/Latinx. Objective: To test the feasibility...
3.
Cuccaro M, Manrique C, Quintero M, Martinez R, McCauley J
Front Genet . 2020 Apr; 11:120. PMID: 32231680
This study examined reasons for participation in a genetic study of risk for multiple sclerosis (MS). Our sample consisted of 101 patients diagnosed with MS who were approached about enrolling...
4.
Nuytemans K, Manrique C, Uhlenberg A, Scott W, Cuccaro M, Luca C, et al.
Front Genet . 2019 Aug; 10:658. PMID: 31379924
Involvement of participants from different racial and ethnic groups in genomic research is vital to reducing health disparities in the precision medicine era. Racial and ethnically diverse populations are underrepresented...
5.
Rajabli F, Feliciano B, Celis K, Hamilton-Nelson K, Whitehead P, Adams L, et al.
PLoS Genet . 2018 Dec; 14(12):e1007791. PMID: 30517106
The ApoE ε4 allele is the most significant genetic risk factor for late-onset Alzheimer disease. The risk conferred by ε4, however, differs across populations, with populations of African ancestry showing...
6.
Hadjixenofontos A, Beecham A, Manrique C, Pericak-Vance M, Tornes L, Ortega M, et al.
Neuroepidemiology . 2015 Jul; 44(4):262-8. PMID: 26184860
Objective: The clinical characteristics of multiple sclerosis (MS) are not well defined in Hispanic populations. We hypothesized that disease presentation in Hispanic white (HW) patients will be different from non-Hispanic...
7.
Beecham A, Patsopoulos N, Xifara D, Davis M, Kemppinen A, Cotsapas C, et al.
Nat Genet . 2013 Oct; 45(11):1353-60. PMID: 24076602
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0...