Clara D Bloomfield
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Explore the profile of Clara D Bloomfield including associated specialties, affiliations and a list of published articles.
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Articles
241
Citations
27097
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Recent Articles
1.
Luskin M, Yin J, Lozanski G, Curran E, Malnassy G, Mrozek K, et al.
Cancer
. 2025 Feb;
131(4):e35750.
PMID: 39916320
Background: Acute lymphoblastic leukemia (ALL) in adults is aggressive, with long-term outcomes impacted by treatment resistance and toxicity. CD52 is expressed in most cases of B- and T-lineage ALL. Alemtuzumab,...
2.
Jahn N, Jahn E, Saadati M, Bullinger L, Larson R, Ottone T, et al.
Leukemia
. 2022 Aug;
36(9):2218-2227.
PMID: 35922444
The aim of this study was to characterize the mutational landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the randomized CALGB 10603/RATIFY trial evaluating intensive chemotherapy plus...
3.
Ferraro F, Miller C, Christensen K, Helton N, OLaughlin M, Fronick C, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(49).
PMID: 34845035
Acute myeloid leukemia (AML) patients rarely have long first remissions (LFRs; >5 y) after standard-of-care chemotherapy, unless classified as favorable risk at presentation. Identification of the mechanisms responsible for long...
4.
Saygin C, Hu E, Zhang P, Sher S, Lozanski A, Doong T, et al.
Leukemia
. 2021 Sep;
35(12):3627.
PMID: 34480107
No abstract available.
5.
Zanetti C, Kumar R, Ender J, Godavarthy P, Hartmann M, Hey J, et al.
Blood
. 2021 Aug;
138(19):1870-1884.
PMID: 34424946
B-cell acute lymphoblastic leukemia (B-ALL) occurs most commonly in children, whereas chronic myeloid leukemia is more frequent in adults. The myeloid bias of hematopoiesis in elderly individuals has been considered...
6.
Rucker F, Du L, Luck T, Benner A, Krzykalla J, Gathmann I, et al.
Leukemia
. 2021 Jul;
36(1):90-99.
PMID: 34316017
In acute myeloid leukemia (AML) internal tandem duplications of the FLT3 gene (FLT3-ITD) are associated with poor prognosis. Retrospectively, we investigated the prognostic and predictive impact of FLT3-ITD insertion site...
7.
Papaioannou D, Ozer H, Nicolet D, Urs A, Herold T, Mrozek K, et al.
Haematologica
. 2021 Jul;
107(5):1034-1044.
PMID: 34261293
Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance...
8.
Walker A, Marcucci G, Yin J, Blum W, Stock W, Kohlschmidt J, et al.
Blood Adv
. 2021 Jul;
5(13):2775-2787.
PMID: 34251414
Overexpression of B-cell leukemia/lymphoma 2 (BCL2) renders acute myeloid leukemia (AML) cells resistant to chemotherapy and has been associated with unfavorable outcomes. Oblimersen (G3139) is a phosphorothioate 18-mer antisense oligonucleotide...
9.
Bill M, Mrozek K, Giacopelli B, Kohlschmidt J, Nicolet D, Papaioannou D, et al.
J Hematol Oncol
. 2021 Jul;
14(1):107.
PMID: 34229733
Recently, a novel knowledge bank (KB) approach to predict outcomes of individual patients with acute myeloid leukemia (AML) was developed using unbiased machine learning. To validate its prognostic value, we...
10.
Mims A, Kohlschmidt J, Borate U, Blachly J, Orwick S, Eisfeld A, et al.
J Hematol Oncol
. 2021 Jun;
14(1):96.
PMID: 34162404
Background: Older patients (≥ 60 years) with acute myeloid leukemia (AML) often have multiple, sequentially acquired, somatic mutations that drive leukemogenesis and are associated with poor outcome. Beat AML is...