Clara Cieza-Borrella
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Explore the profile of Clara Cieza-Borrella including associated specialties, affiliations and a list of published articles.
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762
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Recent Articles
11.
Dadaev T, Saunders E, Newcombe P, Anokian E, Leongamornlert D, Brook M, et al.
Nat Commun
. 2018 Jun;
9(1):2256.
PMID: 29892050
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian...
12.
Schumacher F, Olama A, Berndt S, Benlloch S, Ahmed M, Saunders E, et al.
Nat Genet
. 2018 Jun;
50(7):928-936.
PMID: 29892016
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa...
13.
Perez-Rivera J, Monedero-Campo J, Cieza-Borrella C, Ruiz-Perez P
Expert Opin Drug Metab Toxicol
. 2017 Feb;
13(3):339-350.
PMID: 28135897
Vorapaxar is the first protease-activated receptor-1 inhibitor approved for clinical use. Its main indication is the reduction in thrombotic cardiovascular events in patients with previous myocardial infarction or symptomatic peripheral...
14.
Novo-Veleiro I, Cieza-Borrella C, Pastor I, Chamorro A, Laso F, Gonzalez-Sarmiento R, et al.
PLoS One
. 2016 Dec;
11(12):e0168685.
PMID: 27992614
Background: Genetic polymorphisms in the RAS gene family are associated with different diseases, which may include alcohol-related disorders. Previous studies showed an association of the allelic variant rs26907 in RASGRF2...
15.
Olama A, Dadaev T, Hazelett D, Li Q, Leongamornlert D, Saunders E, et al.
Hum Mol Genet
. 2015 May;
24(19):5589-602.
PMID: 26025378
Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping...
16.
Cieza-Borrella C, Diaz-Soto G, Martinez-Pino I, Puig-Domingo M, Gonzalez-Sarmiento R
J Investig Med
. 2014 Nov;
62(8):968-74.
PMID: 25361053
Purpose: Type 2 diabetes mellitus (type 2 DM) and maturity-onset diabetes of the young present some similar clinical and biochemical characteristics that make them difficult to differentiate. Currently, the polymorphism...
17.
Diez A, Cieza-Borrella C, Suazo V, Gonzalez-Sarmiento R, Papiol S, Molina V
Ann Gen Psychiatry
. 2014 Jul;
13:18.
PMID: 24976857
Background: Neuregulins are a family of signalling proteins that orchestrate a broad range of cellular responses. Four genes encoding Neuregulins 1-4 have been identified so far in vertebrates. Among them,...
18.
de Juan-Marcos L, Escudero-Dominguez F, Hernandez-Galilea E, Cabrillo-Estevez L, Cruz-Gonzalez F, Cieza-Borrella C, et al.
Ophthalmic Genet
. 2014 Jun;
37(1):25-30.
PMID: 24892565
Purpose: To evaluate the association of the lysyl oxidase-like 1 (LOXL1) single nucleotide polymorphisms (SNPs) in a Spanish population with pseudoexfoliation syndrome (XFS) and pseudoexfoliation glaucoma (XFG). Materials And Methods:...
19.
Cruz-Gonzalez F, Cabrillo-Estevez L, Lopez-Valverde G, Cieza-Borrella C, Hernandez-Galilea E, Gonzalez-Sarmiento R
Graefes Arch Clin Exp Ophthalmol
. 2014 Feb;
252(3):469-75.
PMID: 24522370
Background: To determine whether gene polymorphisms of the vascular endothelial growth factor A (VEGF A) and its receptor (VEGFR) influence the response to a variable-dosing treatment regimen with ranibizumab for...
20.
Killick E, Tymrakiewicz M, Cieza-Borrella C, Smith P, Thompson D, Pooley K, et al.
PLoS One
. 2014 Feb;
9(1):e86659.
PMID: 24489760
This study aimed to determine whether telomere length (TL) is a marker of cancer risk or genetic status amongst two cohorts of BRCA1 and BRCA2 mutation carriers and controls. The...