Claire S Whyte
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Explore the profile of Claire S Whyte including associated specialties, affiliations and a list of published articles.
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28
Citations
693
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Recent Articles
1.
Collins P, Whyte C, de Lloyd L, Narwal A, Bell S, Gill N, et al.
Blood Adv
. 2025 Feb;
PMID: 39913691
Haemostatic impairment may exacerbate postpartum haemorrhage (PPH). Previously, we described a distinct coagulopathy, associated with multiple causes of PPH including placental abruption and amniotic fluid embolus, termed acute obstetric coagulopathy...
2.
Sang Y, Lee R, Luong A, Katona E, Whyte C, Smith N, et al.
Blood Adv
. 2024 Aug;
8(19):5072-5085.
PMID: 39116293
Platelet factor XIII-A (FXIII-A) is a major cytoplasmic protein (∼3% of total), representing ∼50% of total circulating FXIII. However, mobilization of FXIII-A during platelet activation is not well defined. To...
3.
Whyte C, Morrow G, Gauer J, Montague S, Nicolson P
Front Cardiovasc Med
. 2023 Sep;
10:1225243.
PMID: 37745127
The 2023 annual meeting of the British Society for Haemostasis and Thrombosis (BSHT) was held in Birmingham, United Kingdom. The theme of this year's meeting was novel therapeutics and emerging...
4.
Simpson M, Narwal A, West E, Martin J, Bagot C, Page A, et al.
J Thromb Haemost
. 2023 Sep;
21(12):3589-3596.
PMID: 37734715
Background: Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare syndrome associated with adenoviral vector vaccines for COVID-19. The syndrome is characterized by thrombosis, anti-platelet factor 4 (PF4) antibodies, thrombocytopenia,...
5.
Mitchell J, Little G, Bye A, Gaspar R, Unsworth A, Kriek N, et al.
Res Pract Thromb Haemost
. 2023 Aug;
7(5):100200.
PMID: 37601014
Background: Factor XIII (FXIII) is an important proenzyme in the hemostatic system. The plasma-derived enzyme activated FXIII cross-links fibrin fibers within thrombi to increase their mechanical strength and cross-links fibrin...
6.
Whyte C
Front Med (Lausanne)
. 2023 Jun;
10:1212201.
PMID: 37332750
The hemostatic and innate immune system are intertwined processes. Inflammation within the vasculature promotes thrombus development, whilst fibrin forms part of the innate immune response to trap invading pathogens. The...
7.
Humphreys S, Whyte C, Mutch N
Front Cardiovasc Med
. 2023 May;
10:1146833.
PMID: 37153474
The superfamily of serine protease inhibitors (SERPINs) are a class of inhibitors that utilise a dynamic conformational change to trap and inhibit their target enzymes. Their powerful nature lends itself...
8.
Jalal M, Whyte C, Coxon F, Mutch N
Platelets
. 2023 May;
34(1):2206921.
PMID: 37139869
Statins inhibit the mevalonate pathway by impairing protein prenylation via depletion of lipid geranylgeranyl diphosphate (GGPP). Rab27b and Rap1a are small GTPase proteins involved in dense granule secretion, platelet activation,...
9.
Whyte C, Panova-Noeva M
Front Cardiovasc Med
. 2023 Mar;
10:1159938.
PMID: 36895837
No abstract available.
10.
Narwal A, Whyte C, Mutch N
Front Cardiovasc Med
. 2023 Feb;
9:1070502.
PMID: 36741833
Thrombi are heterogenous in nature with composition and structure being dictated by the site of formation, initiating stimuli, shear stress, and cellular influences. Arterial thrombi are historically associated with high...