Cierra Carafice
Overview
Explore the profile of Cierra Carafice including associated specialties, affiliations and a list of published articles.
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10
Citations
97
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Recent Articles
1.
Badr A, Daily K, Eltobgy M, Estfanous S, Tan M, Chun-Tien Kuo J, et al.
Brain Behav Immun
. 2024 May;
119:919-944.
PMID: 38718909
Neuroinflammation and accumulation of Amyloid Beta (Aβ) accompanied by deterioration of special memory are hallmarks of Alzheimer's disease (AD). Effective preventative and treatment options for AD are still needed. Microglia...
2.
Daily K, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan M, et al.
Alzheimers Res Ther
. 2024 Feb;
16(1):29.
PMID: 38326859
Alzheimer's disease (AD) is the sixth leading cause of death in the USA. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD...
3.
Daily K, Badr A, Eltobgy M, Estfanous S, Whitham O, Tan M, et al.
bioRxiv
. 2023 Sep;
PMID: 37693600
Alzheimer's Disease (AD) is the 6th leading cause of death in the US. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD...
4.
Eltobgy M, Zani A, Kenney A, Estfanous S, Kim E, Badr A, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(21):e2202012119.
PMID: 35588457
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV-2) is a worldwide health concern, and new treatment strategies are needed. Targeting inflammatory innate immunity pathways holds therapeutic promise, but effective molecular targets...
5.
Badr A, Eltobgy M, Krause K, Hamilton K, Estfanous S, Daily K, et al.
Front Cell Infect Microbiol
. 2022 Mar;
12:819554.
PMID: 35252032
Cystic fibrosis (CF) human and mouse macrophages are defective in their ability to clear bacteria such as . The autophagy process in CF (F508del) macrophages is halted, and the underlying...
6.
Abu Khweek A, Joldrichsen M, Kim E, Attia Z, Krause K, Daily K, et al.
Cell Immunol
. 2021 Nov;
370:104425.
PMID: 34800762
Asthma is an inflammatory lung disorder characterized by mucus hypersecretion, cellular infiltration, and bronchial hyper-responsiveness. House dust mites (HDM) are the most prevalent cause of allergic sensitization. Canonical and noncanonical...
7.
Estfanous S, Daily K, Eltobgy M, Deems N, Anne M, Krause K, et al.
Front Immunol
. 2021 Aug;
12:705581.
PMID: 34426734
Autophagy is a proposed route of amyloid-β (Aβ) clearance by microglia that is halted in Alzheimer's Disease (AD), though mechanisms underlying this dysfunction remain elusive. Here, primary microglia from adult...
8.
Estfanous S, Krause K, Anne M, Eltobgy M, Caution K, Abu Khweek A, et al.
Sci Rep
. 2021 Jun;
11(1):12447.
PMID: 34103646
No abstract available.
9.
Estfanous S, Krause K, Anne M, Eltobgy M, Caution K, Abu Khweek A, et al.
Sci Rep
. 2021 Jan;
11(1):855.
PMID: 33441602
Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients. The lack of gasdermin D (GSDMD) protects mice against...
10.
Hamilton K, Krause K, Badr A, Daily K, Estfanous S, Eltobgy M, et al.
J Cyst Fibros
. 2020 Nov;
20(4):664-672.
PMID: 33208300
Background: Mitochondria play a key role in immune defense pathways, particularly for macrophages. We and others have previously demonstrated that cystic fibrosis (CF) macrophages exhibit weak autophagy activity and exacerbated...