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Churmy Y Fan

Explore the profile of Churmy Y Fan including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 148
Followers 0
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Recent Articles
1.
Fan C, McAllister B, Stokes-Heck S, Harding E, Pereira de Vasconcelos A, Mah L, et al.
Neuron . 2025 Feb; PMID: 39892387
Chronic pain is a leading cause of disability, affecting more women than men. Different immune cells contribute to this sexual divergence, but the mechanisms, especially in females, are not well...
2.
Leduc-Pessah H, Xu C, Fan C, Dalgarno R, Kohro Y, Sparanese S, et al.
J Neurosci Res . 2021 Jun; 100(1):251-264. PMID: 34075613
Opioids are potent analgesics, but their pain-relieving effects diminish with repeated use. The reduction in analgesic potency is a hallmark of opioid analgesic tolerance, which hampers opioid pain therapy. In...
3.
Navis K, Fan C, Trang T, Thompson R, Derksen D
ACS Chem Neurosci . 2020 Jul; 11(15):2163-2172. PMID: 32639715
Pannexin 1 (Panx1) channels are transmembrane proteins that release adenosine triphosphate and play an important role in intercellular communication. They are widely expressed in somatic and nervous system tissues, and...
4.
Leduc-Pessah H, Weilinger N, Fan C, Burma N, Thompson R, Trang T
J Neurosci . 2017 Sep; 37(42):10154-10172. PMID: 28924009
Tolerance to the analgesic effects of opioids is a major problem in chronic pain management. Microglia are implicated in opioid tolerance, but the core mechanisms regulating their response to opioids...
5.
Burke N, Fan C, Trang T
Exp Physiol . 2016 Jul; 101(8):1003-21. PMID: 27474262
What is the topic of this review? This review discusses the origins and development of microglia, and how stress, pain or inflammation in early life disturbs microglial function during critical...
6.
Burma N, Leduc-Pessah H, Fan C, Trang T
J Neurosci Res . 2016 Jul; 95(6):1242-1256. PMID: 27376591
Chronic pain is a global problem that has reached epidemic proportions. An estimated 20% of adults suffer from pain, and another 10% are diagnosed with chronic pain each year (Goldberg...