Chulan Kwon
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Explore the profile of Chulan Kwon including associated specialties, affiliations and a list of published articles.
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73
Citations
1994
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Recent Articles
1.
Kwon C, Gyhm J
Phys Rev E
. 2024 Nov;
110(4-1):044141.
PMID: 39562959
We investigate dynamics of a small quantum system open to a bath with thermostat. We introduce another bath, called a superbath, weakly coupled with the bath to provide it with...
2.
Htet M, Lei S, Bajpayi S, Gangrade H, Arvanitis M, Zoitou A, et al.
Nat Cardiovasc Res
. 2024 Aug;
3(6):666-684.
PMID: 39196225
Cardiomyocyte maturation is crucial for generating adult cardiomyocytes and the application of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs). However, regulation at the cis-regulatory element level and its role in heart...
3.
Li B, Kwon C
bioRxiv
. 2024 Jun;
PMID: 38826381
Blastocyst complementation offers an opportunity for generating transplantable whole organs from donor sources. Pluripotent stem cells (PSCs) have traditionally served as the primary donor cells due to their ability to...
4.
Lee S, Lim G, Kim H, Suh D, Choi H, Kim H, et al.
Stem Cell Res
. 2024 Jun;
78:103453.
PMID: 38824800
Arrhythmogenic cardiomyopathy (ACM) is a cardiomyopathy that is predominantly inherited and characterized by cardiac arrhythmias and structural abnormalities. TMEM43 (transmembrane protein 43) is one of the well-known genetic culprits behind...
5.
Protocol for quantifying stem-cell-derived cardiomyocyte maturity using transcriptomic entropy score
Chen E, Kannan S, Murphy S, Farid M, Kwon C
STAR Protoc
. 2024 May;
5(2):103083.
PMID: 38781077
The inability to quantify cardiomyocyte (CM) maturation remains a significant barrier to evaluating the effects of ongoing efforts to produce adult-like CMs from pluripotent stem cells (PSCs). Here, we present...
6.
Lee S, Lee J, Oh J, Hwang J, Lee H, Byun H, et al.
Cardiovasc Res
. 2024 May;
120(9):1037-1050.
PMID: 38722811
Aims: Doxorubicin (DOX) is a widely used anthracycline anticancer agent; however, its irreversible effects on the heart can result in DOX-induced cardiotoxicity (DICT) after cancer treatment. Unfortunately, the pathophysiology of...
7.
Lo E, Velazquez J, Peng D, Kwon C, Ebrahimkhani M, Cahan P
Stem Cell Reports
. 2023 Jul;
18(8):1721-1742.
PMID: 37478860
Optimization of cell engineering protocols requires standard, comprehensive quality metrics. We previously developed CellNet, a computational tool to quantitatively assess the transcriptional fidelity of engineered cells compared with their natural...
8.
Kervadec A, Kezos J, Ni H, Yu M, Marchant J, Spiering S, et al.
Dis Model Mech
. 2023 Jun;
16(7).
PMID: 37293707
Atrial fibrillation (AF) is a common and genetically inheritable form of cardiac arrhythmia; however, it is currently not known how these genetic predispositions contribute to the initiation and/or maintenance of...
9.
Kannan S, Miyamoto M, Zhu R, Lynott M, Guo J, Chen E, et al.
Cell Rep
. 2023 Apr;
42(4):112330.
PMID: 37014753
A limitation in the application of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) is the failure of these cells to achieve full functional maturity. The mechanisms by which directed differentiation differs from...
10.
Missinato M, Murphy S, Lynott M, Yu M, Kervadec A, Chang Y, et al.
Nat Commun
. 2023 Mar;
14(1):1709.
PMID: 36973293
Defining the mechanisms safeguarding cell fate identity in differentiated cells is crucial to improve 1) - our understanding of how differentiation is maintained in healthy tissues or altered in a...